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Physiological functions of SPP/SPPL intramembrane proteases.
Mentrup T, Cabrera-Cabrera F, Fluhrer R, Schröder B. Mentrup T, et al. Cell Mol Life Sci. 2020 Aug;77(15):2959-2979. doi: 10.1007/s00018-020-03470-6. Epub 2020 Feb 12. Cell Mol Life Sci. 2020. PMID: 32052089 Free PMC article. Review.
The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban.
Niemeyer J, Mentrup T, Heidasch R, Müller SA, Biswas U, Meyer R, Papadopoulou AA, Dederer V, Haug-Kröper M, Adamski V, Lüllmann-Rauch R, Bergmann M, Mayerhofer A, Saftig P, Wennemuth G, Jessberger R, Fluhrer R, Lichtenthaler SF, Lemberg MK, Schröder B. Niemeyer J, et al. Among authors: mentrup t. EMBO Rep. 2019 Mar;20(3):e46449. doi: 10.15252/embr.201846449. Epub 2019 Feb 7. EMBO Rep. 2019. PMID: 30733280 Free PMC article.
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R. Papadopoulou AA, et al. Among authors: mentrup t. EMBO Rep. 2019 Mar;20(3):e46451. doi: 10.15252/embr.201846451. Epub 2019 Feb 7. EMBO Rep. 2019. PMID: 30733281 Free PMC article.
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis.
Mentrup T, Theodorou K, Cabrera-Cabrera F, Helbig AO, Happ K, Gijbels M, Gradtke AC, Rabe B, Fukumori A, Steiner H, Tholey A, Fluhrer R, Donners M, Schröder B. Mentrup T, et al. J Exp Med. 2019 Apr 1;216(4):807-830. doi: 10.1084/jem.20171438. Epub 2019 Feb 28. J Exp Med. 2019. PMID: 30819724 Free PMC article.
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R. Papadopoulou AA, et al. Among authors: mentrup t. EMBO Rep. 2019 May;20(5):e48133. doi: 10.15252/embr.201948133. EMBO Rep. 2019. PMID: 31061204 Free PMC article.
25 results