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Variants of CTGF are associated with hepatic fibrosis in Chinese, Sudanese, and Brazilians infected with schistosomes.
Dessein A, Chevillard C, Arnaud V, Hou X, Hamdoun AA, Dessein H, He H, Abdelmaboud SA, Luo X, Li J, Varoquaux A, Mergani A, Abdelwahed M, Zhou J, Monis A, Pitta MG, Gasmelseed N, Cabantous S, Zhao Y, Prata A, Brandt C, Elwali NE, Argiro L, Li Y. Dessein A, et al. Among authors: mergani a. J Exp Med. 2009 Oct 26;206(11):2321-8. doi: 10.1084/jem.20090383. Epub 2009 Oct 12. J Exp Med. 2009. PMID: 19822645 Free PMC article.
IL-22 and IL-22 binding protein (IL-22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections.
Sertorio M, Hou X, Carmo RF, Dessein H, Cabantous S, Abdelwahed M, Romano A, Albuquerque F, Vasconcelos L, Carmo T, Li J, Varoquaux A, Arnaud V, Oliveira P, Hamdoun A, He H, Adbelmaboud S, Mergani A, Zhou J, Monis A, Pereira LB, Halfon P, Bourlière M, Parana R, Dos Reis M, Gonnelli D, Moura P, Elwali NE, Argiro L, Li Y, Dessein A. Sertorio M, et al. Among authors: mergani a. Hepatology. 2015 Apr;61(4):1321-31. doi: 10.1002/hep.27629. Epub 2015 Mar 10. Hepatology. 2015. PMID: 25476703
Cytokine regulation of periportal fibrosis in humans infected with Schistosoma mansoni: IFN-gamma is associated with protection against fibrosis and TNF-alpha with aggravation of disease.
Henri S, Chevillard C, Mergani A, Paris P, Gaudart J, Camilla C, Dessein H, Montero F, Elwali NE, Saeed OK, Magzoub M, Dessein AJ. Henri S, et al. Among authors: mergani a. J Immunol. 2002 Jul 15;169(2):929-36. doi: 10.4049/jimmunol.169.2.929. J Immunol. 2002. PMID: 12097398
IFN-gamma polymorphisms (IFN-gamma +2109 and IFN-gamma +3810) are associated with severe hepatic fibrosis in human hepatic schistosomiasis (Schistosoma mansoni).
Chevillard C, Moukoko CE, Elwali NE, Bream JH, Kouriba B, Argiro L, Rahoud S, Mergani A, Henri S, Gaudart J, Mohamed-Ali Q, Young HA, Dessein AJ. Chevillard C, et al. Among authors: mergani a. J Immunol. 2003 Nov 15;171(10):5596-601. doi: 10.4049/jimmunol.171.10.5596. J Immunol. 2003. PMID: 14607968
Susceptibility to periportal (Symmers) fibrosis in human schistosoma mansoni infections: evidence that intensity and duration of infection, gender, and inherited factors are critical in disease progression.
Mohamed-Ali Q, Elwali NE, Abdelhameed AA, Mergani A, Rahoud S, Elagib KE, Saeed OK, Abel L, Magzoub MM, Dessein AJ. Mohamed-Ali Q, et al. Among authors: mergani a. J Infect Dis. 1999 Oct;180(4):1298-306. doi: 10.1086/314999. J Infect Dis. 1999. PMID: 10479161
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