Metzler M - Search Results

1

A role for epsin N-terminal homology/AP180 N-terminal homology (ENTH/ANTH) domains in tubulin binding.

Hussain NK, Yamabhai M, Bhakar AL, Metzler M, Ferguson SS, Hayden MR, McPherson PS, Kay BK. Hussain NK, et al. Among authors: metzler m. J Biol Chem. 2003 Aug 1;278(31):28823-30. doi: 10.1074/jbc.M300995200. Epub 2003 May 15. J Biol Chem. 2003. PMID: 12750376 Free article.

2

HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain.

Legendre-Guillemin V, Metzler M, Charbonneau M, Gan L, Chopra V, Philie J, Hayden MR, McPherson PS. Legendre-Guillemin V, et al. Among authors: metzler m. J Biol Chem. 2002 May 31;277(22):19897-904. doi: 10.1074/jbc.M112310200. Epub 2002 Mar 11. J Biol Chem. 2002. PMID: 11889126 Free article.

3

Huntingtin interacting protein 1 (HIP1) regulates clathrin assembly through direct binding to the regulatory region of the clathrin light chain.

Legendre-Guillemin V, Metzler M, Lemaire JF, Philie J, Gan L, Hayden MR, McPherson PS. Legendre-Guillemin V, et al. Among authors: metzler m. J Biol Chem. 2005 Feb 18;280(7):6101-8. doi: 10.1074/jbc.M408430200. Epub 2004 Nov 8. J Biol Chem. 2005. PMID: 15533941 Free article.

4

HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2.

Metzler M, Legendre-Guillemin V, Gan L, Chopra V, Kwok A, McPherson PS, Hayden MR. Metzler M, et al. J Biol Chem. 2001 Oct 19;276(42):39271-6. doi: 10.1074/jbc.C100401200. Epub 2001 Aug 21. J Biol Chem. 2001. PMID: 11517213 Free article.

5

Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domain.

Hackam AS, Yassa AS, Singaraja R, Metzler M, Gutekunst CA, Gan L, Warby S, Wellington CL, Vaillancourt J, Chen N, Gervais FG, Raymond L, Nicholson DW, Hayden MR. Hackam AS, et al. Among authors: metzler m. J Biol Chem. 2000 Dec 29;275(52):41299-308. doi: 10.1074/jbc.M008408200. J Biol Chem. 2000. PMID: 11007801 Free article.

6

Structural abnormalities in spermatids together with reduced sperm counts and motility underlie the reproductive defect in HIP1-/- mice.

Khatchadourian K, Smith CE, Metzler M, Gregory M, Hayden MR, Cyr DG, Hermo L. Khatchadourian K, et al. Among authors: metzler m. Mol Reprod Dev. 2007 Mar;74(3):341-59. doi: 10.1002/mrd.20564. Mol Reprod Dev. 2007. PMID: 16967501

7

Hippi is essential for node cilia assembly and Sonic hedgehog signaling.

Houde C, Dickinson RJ, Houtzager VM, Cullum R, Montpetit R, Metzler M, Simpson EM, Roy S, Hayden MR, Hoodless PA, Nicholson DW. Houde C, et al. Among authors: metzler m. Dev Biol. 2006 Dec 15;300(2):523-33. doi: 10.1016/j.ydbio.2006.09.001. Epub 2006 Sep 9. Dev Biol. 2006. PMID: 17027958 Free PMC article.

8

Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking.

Metzler M, Li B, Gan L, Georgiou J, Gutekunst CA, Wang Y, Torre E, Devon RS, Oh R, Legendre-Guillemin V, Rich M, Alvarez C, Gertsenstein M, McPherson PS, Nagy A, Wang YT, Roder JC, Raymond LA, Hayden MR. Metzler M, et al. EMBO J. 2003 Jul 1;22(13):3254-66. doi: 10.1093/emboj/cdg334. EMBO J. 2003. PMID: 12839988 Free PMC article.

9

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.

Gervais FG, Singaraja R, Xanthoudakis S, Gutekunst CA, Leavitt BR, Metzler M, Hackam AS, Tam J, Vaillancourt JP, Houtzager V, Rasper DM, Roy S, Hayden MR, Nicholson DW. Gervais FG, et al. Among authors: metzler m. Nat Cell Biol. 2002 Feb;4(2):95-105. doi: 10.1038/ncb735. Nat Cell Biol. 2002. PMID: 11788820

10

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis.

Singaraja RR, Hadano S, Metzler M, Givan S, Wellington CL, Warby S, Yanai A, Gutekunst CA, Leavitt BR, Yi H, Fichter K, Gan L, McCutcheon K, Chopra V, Michel J, Hersch SM, Ikeda JE, Hayden MR. Singaraja RR, et al. Among authors: metzler m. Hum Mol Genet. 2002 Nov 1;11(23):2815-28. doi: 10.1093/hmg/11.23.2815. Hum Mol Genet. 2002. PMID: 12393793

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