Michaelis S - Search Results

1

Therapeutic intervention based on protein prenylation and associated modifications.

Gelb MH, Brunsveld L, Hrycyna CA, Michaelis S, Tamanoi F, Van Voorhis WC, Waldmann H. Gelb MH, et al. Among authors: michaelis s. Nat Chem Biol. 2006 Oct;2(10):518-28. doi: 10.1038/nchembio818. Nat Chem Biol. 2006. PMID: 16983387 Free PMC article. Review.

2

Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome.

Mallampalli MP, Huyer G, Bendale P, Gelb MH, Michaelis S. Mallampalli MP, et al. Among authors: michaelis s. Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14416-21. doi: 10.1073/pnas.0503712102. Epub 2005 Sep 26. Proc Natl Acad Sci U S A. 2005. PMID: 16186497 Free PMC article.

3

ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability.

Spear ED, Hsu ET, Nie L, Carpenter EP, Hrycyna CA, Michaelis S. Spear ED, et al. Among authors: michaelis s. Dis Model Mech. 2018 Jul 13;11(7):dmm033670. doi: 10.1242/dmm.033670. Dis Model Mech. 2018. PMID: 29794150 Free PMC article.

4

Human ZMPSTE24 disease mutations: residual proteolytic activity correlates with disease severity.

Barrowman J, Wiley PA, Hudon-Miller SE, Hrycyna CA, Michaelis S. Barrowman J, et al. Among authors: michaelis s. Hum Mol Genet. 2012 Sep 15;21(18):4084-93. doi: 10.1093/hmg/dds233. Epub 2012 Jun 19. Hum Mol Genet. 2012. PMID: 22718200 Free PMC article.

5

Biochemistry. A protease for the ages.

Michaelis S, Hrycyna CA. Michaelis S, et al. Science. 2013 Mar 29;339(6127):1529-30. doi: 10.1126/science.1236764. Science. 2013. PMID: 23539586 No abstract available.

6

Purification, functional reconstitution, and characterization of the Saccharomyces cerevisiae isoprenylcysteine carboxylmethyltransferase Ste14p.

Anderson JL, Frase H, Michaelis S, Hrycyna CA. Anderson JL, et al. Among authors: michaelis s. J Biol Chem. 2005 Feb 25;280(8):7336-45. doi: 10.1074/jbc.M410292200. Epub 2004 Dec 20. J Biol Chem. 2005. PMID: 15611058 Free article.

7

HIV-protease inhibitors block the enzymatic activity of purified Ste24p.

Hudon SE, Coffinier C, Michaelis S, Fong LG, Young SG, Hrycyna CA. Hudon SE, et al. Among authors: michaelis s. Biochem Biophys Res Commun. 2008 Sep 19;374(2):365-8. doi: 10.1016/j.bbrc.2008.07.033. Epub 2008 Jul 17. Biochem Biophys Res Commun. 2008. PMID: 18639527 Free PMC article.

8

The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins.

Hrycyna CA, Sapperstein SK, Clarke S, Michaelis S. Hrycyna CA, et al. Among authors: michaelis s. EMBO J. 1991 Jul;10(7):1699-709. doi: 10.1002/j.1460-2075.1991.tb07694.x. EMBO J. 1991. PMID: 2050108 Free PMC article.

9

Yeast STE14 methyltransferase, expressed as TrpE-STE14 fusion protein in Escherichia coli, for in vitro carboxylmethylation of prenylated polypeptides.

Hrycyna CA, Wait SJ, Backlund PS Jr, Michaelis S. Hrycyna CA, et al. Among authors: michaelis s. Methods Enzymol. 1995;250:251-66. doi: 10.1016/0076-6879(95)50077-4. Methods Enzymol. 1995. PMID: 7651156 No abstract available.

10

Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24.

Corrigan DP, Kuszczak D, Rusinol AE, Thewke DP, Hrycyna CA, Michaelis S, Sinensky MS. Corrigan DP, et al. Among authors: michaelis s. Biochem J. 2005 Apr 1;387(Pt 1):129-38. doi: 10.1042/BJ20041359. Biochem J. 2005. PMID: 15479156 Free PMC article.

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