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Seasonal Chemical Evaluation of Miconia chamissois Naudin from Brazilian Savanna.
Ferreira JF, López MHM, Gomes JVD, Martins DHN, Fagg CW, Magalhães PO, Davies NW, Silveira D, Fonseca-Bazzo YM. Ferreira JF, et al. Molecules. 2022 Feb 8;27(3):1120. doi: 10.3390/molecules27031120. Molecules. 2022. PMID: 35164385 Free PMC article.
Miconia chamissois Naudin is a species from the Cerrado, which is being increasingly researched for its therapeutic potential. ...These results showed that it is possible to obtain extracts from M. chamissois at any time of the year without significant differ
Miconia chamissois Naudin is a species from the Cerrado, which is being increasingly researched for its therapeutic potential.
Matteucinol, isolated from Miconia chamissois, induces apoptosis in human glioblastoma lines via the intrinsic pathway and inhibits angiogenesis and tumor growth in vivo.
Silva AG, Silva VAO, Oliveira RJS, de Rezende AR, Chagas RCR, Pimenta LPS, Romão W, Santos HB, Thomé RG, Reis RM, de Azambuja Ribeiro RIM. Silva AG, et al. Invest New Drugs. 2020 Aug;38(4):1044-1055. doi: 10.1007/s10637-019-00878-1. Epub 2019 Nov 28. Invest New Drugs. 2020. PMID: 31781904
This study was conducted to investigate the antitumor potential (in vitro and in vivo) of Miconia chamissois Naudin for treating glioblastomas. We investigated the cytotoxicity of the chloroform partition and its sub-fraction in glioblastoma cell lines (GAMG and U25 …
This study was conducted to investigate the antitumor potential (in vitro and in vivo) of Miconia chamissois Naudin for treati …
Phytotoxicity of organic extracts of five medicinal plants of the Neotropical savanna.
Pinto GFS, Roma LP, Kolb RM. Pinto GFS, et al. Braz J Biol. 2023 Apr 17;83:e270122. doi: 10.1590/1519-6984.270122. eCollection 2023. Braz J Biol. 2023. PMID: 37075426 Free article.
We analyzed the phytotoxic activity of organic extracts from the leaves of five medicinal species, Byrsonima intermedia, Moquiniastrum polymorphum, Luehea candicans, Miconia chamissois, and Qualea cordata. Phytotoxicity was evaluated on the initial growth of cucumbe …
We analyzed the phytotoxic activity of organic extracts from the leaves of five medicinal species, Byrsonima intermedia, Moquiniastrum polym …
Bioprospecting of Natural Compounds from Brazilian Cerrado Biome Plants in Human Cervical Cancer Cell Lines.
Rosa MN, E Silva LRV, Longato GB, Evangelista AF, Gomes INF, Alves ALV, de Oliveira BG, Pinto FE, Romão W, de Rezende AR, Araújo AAC, Oliveira LSFM, de M Souza AA, Oliveira SC, de A Ribeiro RIM, Silva VAO, Reis RM. Rosa MN, et al. Int J Mol Sci. 2021 Mar 25;22(7):3383. doi: 10.3390/ijms22073383. Int J Mol Sci. 2021. PMID: 33806119 Free PMC article.
The effect of crude extracts on cell viability was evaluated by a colorimetric method (MTS assay). Extracts from Annona crassiflora, Miconia albicans, Miconia chamissois, Stryphnodendron adstringens, Tapirira guianensis, Xylopia aromatica, and Achyrocline ala …
The effect of crude extracts on cell viability was evaluated by a colorimetric method (MTS assay). Extracts from Annona crassiflora, Mico
Bio-Prospecting of Crude Leaf Extracts from Thirteen Plants of Brazilian Cerrado Biome on Human Glioma Cell Lines.
Silva VAO, Rosa MN, Gomes INF, Vital PDS, Alves ALV, Evangelista AF, Longato GB, Carloni AC, Oliveira BG, Pinto FE, Romão W, Rezende AR, Araújo AAC, Oliveira LSFM, Souza AAM, Oliveira SC, Ribeiro RIMA, Reis RM. Silva VAO, et al. Molecules. 2023 Feb 1;28(3):1394. doi: 10.3390/molecules28031394. Molecules. 2023. PMID: 36771057 Free PMC article.
Mass spectrometry (ESI FT-ICR MS) was performed to identify the secondary metabolites classes presented in the crude extracts and partitions. (4) Results: Our results revealed the cytotoxic potential of Melastomataceae species Miconia cuspidata, Miconia albic …
Mass spectrometry (ESI FT-ICR MS) was performed to identify the secondary metabolites classes presented in the crude extracts and partitions …
Matteucinol combined with temozolomide inhibits glioblastoma proliferation, invasion, and progression: an in vitro, in silico, and in vivo study.
Netto JB, Melo ESA, Oliveira AGS, Sousa LR, Santiago LR, Santos DM, Chagas RCR, Gonçalves AS, Thomé RG, Santos HB, Reis RM, Ribeiro RIMA. Netto JB, et al. Braz J Med Biol Res. 2022 Aug 22;55:e12076. doi: 10.1590/1414-431X2022e12076. eCollection 2022. Braz J Med Biol Res. 2022. PMID: 36000612 Free PMC article.
Here, we aimed to investigate the anti-glioblastoma effect of the combination of matteucinol (Mat) (dihydroxyflavanone derived from Miconia chamissois Naudin) with the chemotherapeutic TMZ in vitro using tumor (U-251MG) and normal astrocyte (NHA) cell lines and in v …
Here, we aimed to investigate the anti-glioblastoma effect of the combination of matteucinol (Mat) (dihydroxyflavanone derived from Micon