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Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma.
Middleton MR, Grob JJ, Aaronson N, Fierlbeck G, Tilgen W, Seiter S, Gore M, Aamdal S, Cebon J, Coates A, Dreno B, Henz M, Schadendorf D, Kapp A, Weiss J, Fraass U, Statkevich P, Muller M, Thatcher N. Middleton MR, et al. J Clin Oncol. 2000 Jan;18(1):158-66. doi: 10.1200/JCO.2000.18.1.158. J Clin Oncol. 2000. PMID: 10623706 Clinical Trial.
Brain metastases in melanoma: a European perspective.
Cattell E, Kelly C, Middleton MR. Cattell E, et al. Among authors: middleton mr. Semin Oncol. 2002 Oct;29(5):513-7. doi: 10.1053/sonc.2002.35246. Semin Oncol. 2002. PMID: 12407516 Review.
Temozolomide pharmacodynamics in patients with metastatic melanoma: dna damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1.
Plummer ER, Middleton MR, Jones C, Olsen A, Hickson I, McHugh P, Margison GP, McGown G, Thorncroft M, Watson AJ, Boddy AV, Calvert AH, Harris AL, Newell DR, Curtin NJ. Plummer ER, et al. Among authors: middleton mr. Clin Cancer Res. 2005 May 1;11(9):3402-9. doi: 10.1158/1078-0432.CCR-04-2353. Clin Cancer Res. 2005. PMID: 15867241 Free article. Clinical Trial.
Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group.
Gogas H, Polyzos A, Stavrinidis I, Frangia K, Tsoutsos D, Panagiotou P, Markopoulos C, Papadopoulos O, Pectasides D, Mantzourani M, Middleton M, Vaiopoulos G, Fountzilas G. Gogas H, et al. Ann Oncol. 2006 Dec;17(12):1835-41. doi: 10.1093/annonc/mdl311. Epub 2006 Sep 15. Ann Oncol. 2006. PMID: 16980601 Free article. Clinical Trial.
Randomized trial of the combination of lomeguatrib and temozolomide compared with temozolomide alone in chemotherapy naive patients with metastatic cutaneous melanoma.
Ranson M, Hersey P, Thompson D, Beith J, McArthur GA, Haydon A, Davis ID, Kefford RF, Mortimer P, Harris PA, Baka S, Seebaran A, Sabharwal A, Watson AJ, Margison GP, Middleton MR. Ranson M, et al. Among authors: middleton mr. J Clin Oncol. 2007 Jun 20;25(18):2540-5. doi: 10.1200/JCO.2007.10.8217. J Clin Oncol. 2007. PMID: 17577032 Clinical Trial.
234 results