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Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis.
Nielsen SR, Quaranta V, Linford A, Emeagi P, Rainer C, Santos A, Ireland L, Sakai T, Sakai K, Kim YS, Engle D, Campbell F, Palmer D, Ko JH, Tuveson DA, Hirsch E, Mielgo A, Schmid MC. Nielsen SR, et al. Among authors: mielgo a. Nat Cell Biol. 2016 May;18(5):549-60. doi: 10.1038/ncb3340. Epub 2016 Apr 18. Nat Cell Biol. 2016. PMID: 27088855 Free PMC article.
Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors.
Ireland L, Santos A, Ahmed MS, Rainer C, Nielsen SR, Quaranta V, Weyer-Czernilofsky U, Engle DD, Perez-Mancera PA, Coupland SE, Taktak A, Bogenrieder T, Tuveson DA, Campbell F, Schmid MC, Mielgo A. Ireland L, et al. Among authors: mielgo a. Cancer Res. 2016 Dec 1;76(23):6851-6863. doi: 10.1158/0008-5472.CAN-16-1201. Epub 2016 Oct 14. Cancer Res. 2016. PMID: 27742686 Free PMC article.
Blockade of MIF-CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma.
Figueiredo CR, Azevedo RA, Mousdell S, Resende-Lara PT, Ireland L, Santos A, Girola N, Cunha RLOR, Schmid MC, Polonelli L, Travassos LR, Mielgo A. Figueiredo CR, et al. Among authors: mielgo a. Front Immunol. 2018 May 23;9:1132. doi: 10.3389/fimmu.2018.01132. eCollection 2018. Front Immunol. 2018. PMID: 29875777 Free PMC article.
Liver Tropism in Cancer: The Hepatic Metastatic Niche.
Mielgo A, Schmid MC. Mielgo A, et al. Cold Spring Harb Perspect Med. 2020 Mar 2;10(3):a037259. doi: 10.1101/cshperspect.a037259. Cold Spring Harb Perspect Med. 2020. PMID: 31548227 Free PMC article. Review.
61 results