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HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence.
Cui M, Yamano K, Yamamoto K, Yamamoto-Imoto H, Minami S, Yamamoto T, Matsui S, Kaminishi T, Shima T, Ogura M, Tsuchiya M, Nishino K, Layden BT, Kato H, Ogawa H, Oki S, Okada Y, Isaka Y, Kosako H, Matsuda N, Yoshimori T, Nakamura S. Cui M, et al. Among authors: minami s. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2306454120. doi: 10.1073/pnas.2306454120. Epub 2024 Jan 3. Proc Natl Acad Sci U S A. 2024. PMID: 38170752
LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury.
Nakamura S, Shigeyama S, Minami S, Shima T, Akayama S, Matsuda T, Esposito A, Napolitano G, Kuma A, Namba-Hamano T, Nakamura J, Yamamoto K, Sasai M, Tokumura A, Miyamoto M, Oe Y, Fujita T, Terawaki S, Takahashi A, Hamasaki M, Yamamoto M, Okada Y, Komatsu M, Nagai T, Takabatake Y, Xu H, Isaka Y, Ballabio A, Yoshimori T. Nakamura S, et al. Among authors: minami s. Nat Cell Biol. 2020 Oct;22(10):1252-1263. doi: 10.1038/s41556-020-00583-9. Epub 2020 Sep 28. Nat Cell Biol. 2020. PMID: 32989250
Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis.
Yamamoto-Imoto H, Minami S, Shioda T, Yamashita Y, Sakai S, Maeda S, Yamamoto T, Oki S, Takashima M, Yamamuro T, Yanagawa K, Edahiro R, Iwatani M, So M, Tokumura A, Abe T, Imamura R, Nonomura N, Okada Y, Ayer DE, Ogawa H, Hara E, Takabatake Y, Isaka Y, Nakamura S, Yoshimori T. Yamamoto-Imoto H, et al. Among authors: minami s. Cell Rep. 2022 Mar 1;38(9):110444. doi: 10.1016/j.celrep.2022.110444. Cell Rep. 2022. PMID: 35235784 Free article.
TFEB-mediated lysosomal exocytosis alleviates high-fat diet-induced lipotoxicity in the kidney.
Nakamura J, Yamamoto T, Takabatake Y, Namba-Hamano T, Minami S, Takahashi A, Matsuda J, Sakai S, Yonishi H, Maeda S, Matsui S, Matsui I, Hamano T, Takahashi M, Goto M, Izumi Y, Bamba T, Sasai M, Yamamoto M, Matsusaka T, Niimura F, Yanagita M, Nakamura S, Yoshimori T, Ballabio A, Isaka Y. Nakamura J, et al. Among authors: minami s. JCI Insight. 2023 Feb 22;8(4):e162498. doi: 10.1172/jci.insight.162498. JCI Insight. 2023. PMID: 36649084 Free PMC article.
Rubicon in Metabolic Diseases and Ageing.
Minami S, Nakamura S, Yoshimori T. Minami S, et al. Front Cell Dev Biol. 2022 Jan 10;9:816829. doi: 10.3389/fcell.2021.816829. eCollection 2021. Front Cell Dev Biol. 2022. PMID: 35083223 Free PMC article. Review.
Autophagy and kidney aging.
Minami S, Yamamoto T, Yamamoto-Imoto H, Isaka Y, Hamasaki M. Minami S, et al. Prog Biophys Mol Biol. 2023 May;179:10-15. doi: 10.1016/j.pbiomolbio.2023.02.005. Epub 2023 Feb 26. Prog Biophys Mol Biol. 2023. PMID: 36849016 Review.
Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule.
Yamamoto T, Takabatake Y, Kimura T, Takahashi A, Namba T, Matsuda J, Minami S, Kaimori JY, Matsui I, Kitamura H, Matsusaka T, Niimura F, Yanagita M, Isaka Y, Rakugi H. Yamamoto T, et al. Among authors: minami s. Autophagy. 2016 May 3;12(5):801-13. doi: 10.1080/15548627.2016.1159376. Epub 2016 Mar 17. Autophagy. 2016. PMID: 26986194 Free PMC article.
1,295 results