Minkkilä A - Search Results

1

Characterization of binding properties of monoglyceride lipase inhibitors by a versatile fluorescence-based technique.

Savinainen JR, Yoshino M, Minkkilä A, Nevalainen T, Laitinen JT. Savinainen JR, et al. Among authors: minkkila a. Anal Biochem. 2010 Apr 1;399(1):132-4. doi: 10.1016/j.ab.2009.12.009. Epub 2009 Dec 11. Anal Biochem. 2010. PMID: 20005861

2

Screening of various hormone-sensitive lipase inhibitors as endocannabinoid-hydrolyzing enzyme inhibitors.

Minkkilä A, Savinainen JR, Käsnänen H, Xhaard H, Nevalainen T, Laitinen JT, Poso A, Leppänen J, Saario SM. Minkkilä A, et al. ChemMedChem. 2009 Aug;4(8):1253-9. doi: 10.1002/cmdc.200900137. ChemMedChem. 2009. PMID: 19472270 No abstract available.

3

Discovery and development of endocannabinoid-hydrolyzing enzyme inhibitors.

Minkkilä A, Saario S, Nevalainen T. Minkkilä A, et al. Curr Top Med Chem. 2010;10(8):828-58. doi: 10.2174/156802610791164238. Curr Top Med Chem. 2010. PMID: 20370710 Review.

4

The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors.

Minkkilä A, Myllymäki MJ, Saario SM, Castillo-Melendez JA, Koskinen AM, Fowler CJ, Leppänen J, Nevalainen T. Minkkilä A, et al. Eur J Med Chem. 2009 Jul;44(7):2994-3008. doi: 10.1016/j.ejmech.2009.01.007. Epub 2009 Jan 20. Eur J Med Chem. 2009. PMID: 19232787

5

1,3,4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity determinants by molecular modelling.

Käsnänen H, Minkkilä A, Taupila S, Patel JZ, Parkkari T, Lahtela-Kakkonen M, Saario SM, Nevalainen T, Poso A. Käsnänen H, et al. Among authors: minkkila a. Eur J Pharm Sci. 2013 Jun 14;49(3):423-33. doi: 10.1016/j.ejps.2013.03.015. Epub 2013 Apr 2. Eur J Pharm Sci. 2013. PMID: 23557840

6

Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase.

Minkkilä A, Saario SM, Käsnänen H, Leppänen J, Poso A, Nevalainen T. Minkkilä A, et al. J Med Chem. 2008 Nov 27;51(22):7057-60. doi: 10.1021/jm801051t. J Med Chem. 2008. PMID: 18983140

7

3-Heterocycle-phenyl N-alkylcarbamates as FAAH inhibitors: design, synthesis and 3D-QSAR studies.

Käsnänen H, Myllymäki MJ, Minkkilä A, Kataja AO, Saario SM, Nevalainen T, Koskinen AM, Poso A. Käsnänen H, et al. Among authors: minkkila a. ChemMedChem. 2010 Feb 1;5(2):213-31. doi: 10.1002/cmdc.200900390. ChemMedChem. 2010. PMID: 20024981

8

The medicinal chemistry of endocannabinoid system 25 Jan.

Nevalainen T, Minkkilä A. Nevalainen T, et al. Among authors: minkkila a. Curr Top Med Chem. 2010;10(8):767. doi: 10.2174/156802610791164247. Curr Top Med Chem. 2010. PMID: 20482503 No abstract available.

9

Bisoxazoline-Lewis acid-catalyzed direct-electron demand oxo-hetero-Diels-Alder reactions of N-oxy-pyridine aldehyde and ketone derivatives.

Landa A, Richter B, Johansen RL, Minkkilä A, Jørgensen KA. Landa A, et al. Among authors: minkkila a. J Org Chem. 2007 Jan 5;72(1):240-5. doi: 10.1021/jo062012u. J Org Chem. 2007. PMID: 17194105

10

Bis(oxazoline) Lewis acid catalyzed aldol reactions of pyridine N-oxide aldehydes--synthesis of optically active 2-(1-hydroxyalkyl)pyridine derivatives: development, scope, and total synthesis of an indolizine alkaloid.

Landa A, Minkkilä A, Blay G, Jørgensen KA. Landa A, et al. Among authors: minkkila a. Chemistry. 2006 Apr 24;12(13):3472-83. doi: 10.1002/chem.200501475. Chemistry. 2006. PMID: 16548019

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