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A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation.
Chapman RW, Minnicozzi M, Celly CS, Phillips JE, Kung TT, Hipkin RW, Fan X, Rindgen D, Deno G, Bond R, Gonsiorek W, Billah MM, Fine JS, Hey JA. Chapman RW, et al. Among authors: minnicozzi m. J Pharmacol Exp Ther. 2007 Aug;322(2):486-93. doi: 10.1124/jpet.106.119040. Epub 2007 May 11. J Pharmacol Exp Ther. 2007. PMID: 17496165
Inhibition of experimental acute pulmonary inflammation by pirfenidone.
Spond J, Case N, Chapman RW, Crawley Y, Egan RW, Fine J, Hey JA, Kreutner W, Kung T, Wang P, Minnicozzi M. Spond J, et al. Among authors: minnicozzi m. Pulm Pharmacol Ther. 2003;16(4):207-14. doi: 10.1016/S1094-5539(03)00026-9. Pulm Pharmacol Ther. 2003. PMID: 12850123
Pharmacology of N-(3,5-dichloro-1-oxido-4-pyridinyl)-8-methoxy-2-(trifluoromethyl)-5-quinoline carboxamide (SCH 351591), a novel, orally active phosphodiesterase 4 inhibitor.
Billah MM, Cooper N, Minnicozzi M, Warneck J, Wang P, Hey JA, Kreutner W, Rizzo CA, Smith SR, Young S, Chapman RW, Dyke H, Shih NY, Piwinski JJ, Cuss FM, Montana J, Ganguly AK, Egan RW. Billah MM, et al. Among authors: minnicozzi m. J Pharmacol Exp Ther. 2002 Jul;302(1):127-37. doi: 10.1124/jpet.302.1.127. J Pharmacol Exp Ther. 2002. PMID: 12065709 Clinical Trial.
Role of nitric oxide on eosinophilic lung inflammation in allergic mice.
Feder LS, Stelts D, Chapman RW, Manfra D, Crawley Y, Jones H, Minnicozzi M, Fernandez X, Paster T, Egan RW, Kreutner W, Kung TT. Feder LS, et al. Among authors: minnicozzi m. Am J Respir Cell Mol Biol. 1997 Oct;17(4):436-42. doi: 10.1165/ajrcmb.17.4.2845. Am J Respir Cell Mol Biol. 1997. PMID: 9376118
Effect of Sch 55700, a humanized monoclonal antibody to human interleukin-5, on eosinophilic responses and bronchial hyperreactivity.
Egan RW, Athwal D, Bodmer MW, Carter JM, Chapman RW, Chou CC, Cox MA, Emtage JS, Fernandez X, Genatt N, Indelicato SR, Jenh CH, Kreutner W, Kung TT, Mauser PJ, Minnicozzi M, Murgolo NJ, Narula SK, Petro ME, Schilling A, Sehring S, Stelts D, Stephens S, Taremi SS, Zurcher J, et al. Egan RW, et al. Among authors: minnicozzi m. Arzneimittelforschung. 1999 Sep;49(9):779-90. doi: 10.1055/s-0031-1300502. Arzneimittelforschung. 1999. PMID: 10514907
42 results