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Design of Novel 3-Pyrimidinylazaindole CDK2/9 Inhibitors with Potent In Vitro and In Vivo Antitumor Efficacy in a Triple-Negative Breast Cancer Model.
Singh U, Chashoo G, Khan SU, Mahajan P, Nargotra A, Mahajan G, Singh A, Sharma A, Mintoo MJ, Guru SK, Aruri H, Thatikonda T, Sahu P, Chibber P, Kumar V, Mir SA, Bharate SS, Madishetti S, Nandi U, Singh G, Mondhe DM, Bhushan S, Malik F, Mignani S, Vishwakarma RA, Singh PP. Singh U, et al. Among authors: mintoo mj. J Med Chem. 2017 Dec 14;60(23):9470-9489. doi: 10.1021/acs.jmedchem.7b00663. Epub 2017 Dec 5. J Med Chem. 2017. PMID: 29144137
Antitumour, acute toxicity and molecular modeling studies of 4-(pyridin-4-yl)-6-(thiophen-2-yl) pyrimidin-2(1H)-one against Ehrlich ascites carcinoma and sarcoma-180.
Kumar D, Sharma P, Nepali K, Mahajan G, Mintoo MJ, Singh A, Singh G, Mondhe DM, Singh G, Jain SK, Gupta GK, Ntie-Kang F. Kumar D, et al. Among authors: mintoo mj. Heliyon. 2018 Jun 27;4(6):e00661. doi: 10.1016/j.heliyon.2018.e00661. eCollection 2018 Jun. Heliyon. 2018. PMID: 30003157 Free PMC article.
Exploring Derivatives of Quinazoline Alkaloid l-Vasicine as Cap Groups in the Design and Biological Mechanistic Evaluation of Novel Antitumor Histone Deacetylase Inhibitors.
Ahmad M, Aga MA, Bhat JA, Kumar B, Rouf A, Capalash N, Mintoo MJ, Kumar A, Mahajan P, Mondhe DM, Nargotra A, Sharma PR, Zargar MA, Vishwakarma RA, Shah BA, Taneja SC, Hamid A. Ahmad M, et al. Among authors: mintoo mj. J Med Chem. 2017 Apr 27;60(8):3484-3497. doi: 10.1021/acs.jmedchem.7b00322. Epub 2017 Apr 13. J Med Chem. 2017. PMID: 28368585
Inhibition of phosphotidylinositol-3 kinase pathway by a novel naphthol derivative of betulinic acid induces cell cycle arrest and apoptosis in cancer cells of different origin.
Majeed R, Hamid A, Sangwan PL, Chinthakindi PK, Koul S, Rayees S, Singh G, Mondhe DM, Mintoo MJ, Singh SK, Rath SK, Saxena AK. Majeed R, et al. Among authors: mintoo mj. Cell Death Dis. 2014 Oct 9;5(10):e1459. doi: 10.1038/cddis.2014.387. Cell Death Dis. 2014. PMID: 25299784 Free PMC article.
24 results