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Impact of mono- and di-β-galactose moieties in in vitro / in vivo anticancer efficacy of pyropheophorbide-carbohydrate conjugates by photodynamic therapy.
Dukh M, Cacaccio J, Durrani FA, Kumar I, Watson R, Tabaczynski WA, Joshi P, Missert JR, Baumann H, Pandey RK. Dukh M, et al. Among authors: missert jr. Eur J Med Chem Rep. 2022 Aug;5:100047. doi: 10.1016/j.ejmcr.2022.100047. Epub 2022 Apr 18. Eur J Med Chem Rep. 2022. PMID: 36568335 Free PMC article.
In vitro cellular uptake and dimerization of signal transducer and activator of transcription-3 (STAT3) identify the photosensitizing and imaging-potential of isomeric photosensitizers derived from chlorophyll-a and bacteriochlorophyll-a.
Srivatsan A, Wang Y, Joshi P, Sajjad M, Chen Y, Liu C, Thankppan K, Missert JR, Tracy E, Morgan J, Rigual N, Baumann H, Pandey RK. Srivatsan A, et al. Among authors: missert jr. J Med Chem. 2011 Oct 13;54(19):6859-73. doi: 10.1021/jm200805y. Epub 2011 Sep 6. J Med Chem. 2011. PMID: 21842893 Free PMC article.
Highly Effective Dual-Function Near-Infrared (NIR) Photosensitizer for Fluorescence Imaging and Photodynamic Therapy (PDT) of Cancer.
Patel N, Pera P, Joshi P, Dukh M, Tabaczynski WA, Siters KE, Kryman M, Cheruku RR, Durrani F, Missert JR, Watson R, Ohulchanskyy TY, Tracy EC, Baumann H, Pandey RK. Patel N, et al. Among authors: missert jr. J Med Chem. 2016 Nov 10;59(21):9774-9787. doi: 10.1021/acs.jmedchem.6b00890. Epub 2016 Oct 31. J Med Chem. 2016. PMID: 27749069
Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer.
Cheruku RR, Cacaccio J, Durrani FA, Tabaczynski WA, Watson R, Siters K, Missert JR, Tracy EC, Dukh M, Guru K, Koya RC, Kalinski P, Baumann H, Pandey RK. Cheruku RR, et al. Among authors: missert jr. J Med Chem. 2021 Jan 14;64(1):741-767. doi: 10.1021/acs.jmedchem.0c01735. Epub 2021 Jan 5. J Med Chem. 2021. PMID: 33400524 Free PMC article.
Tumor-Avid 3-(1'-Hexyloxy)ethyl-3-devinylpyrpyropheophorbide-a (HPPH)-3Gd(III)tetraxetan (DOTA) Conjugate Defines Primary Tumors and Metastases.
Cheruku RR, Turowski SG, Durrani FA, Tabaczynski WA, Cacaccio J, Missert JR, Curtin L, Sexton S, Alberico R, Hendler CM, Spernyak JA, Grossman Z, Pandey RK. Cheruku RR, et al. Among authors: missert jr. J Med Chem. 2022 Jul 14;65(13):9267-9280. doi: 10.1021/acs.jmedchem.2c00547. Epub 2022 Jun 28. J Med Chem. 2022. PMID: 35763292
Synthesis, photophysical properties, tumor uptake, and preliminary in vivo photosensitizing efficacy of a homologous series of 3-(1'-alkyloxy)ethyl-3-devinylpurpurin-18-N-alkylimides with variable lipophilicity.
Zheng G, Potter WR, Camacho SH, Missert JR, Wang G, Bellnier DA, Henderson BW, Rodgers MA, Dougherty TJ, Pandey RK. Zheng G, et al. Among authors: missert jr. J Med Chem. 2001 May 10;44(10):1540-59. doi: 10.1021/jm0005510. J Med Chem. 2001. PMID: 11334564
44 results