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Analgesic exposure in pregnant rats affects fetal germ cell development with inter-generational reproductive consequences.
Dean A, van den Driesche S, Wang Y, McKinnell C, Macpherson S, Eddie SL, Kinnell H, Hurtado-Gonzalez P, Chambers TJ, Stevenson K, Wolfinger E, Hrabalkova L, Calarrao A, Bayne RA, Hagen CP, Mitchell RT, Anderson RA, Sharpe RM. Dean A, et al. Among authors: mitchell rt. Sci Rep. 2016 Jan 27;6:19789. doi: 10.1038/srep19789. Sci Rep. 2016. PMID: 26813099 Free PMC article.
Proposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodents.
van den Driesche S, Walker M, McKinnell C, Scott HM, Eddie SL, Mitchell RT, Seckl JR, Drake AJ, Smith LB, Anderson RA, Sharpe RM. van den Driesche S, et al. Among authors: mitchell rt. PLoS One. 2012;7(5):e37064. doi: 10.1371/journal.pone.0037064. Epub 2012 May 17. PLoS One. 2012. PMID: 22615892 Free PMC article.
160 results