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Divergent clonal differentiation trajectories establish CD8+ memory T cell heterogeneity during acute viral infections in humans.
Mold JE, Modolo L, Hård J, Zamboni M, Larsson AJM, Stenudd M, Eriksson CJ, Durif G, Ståhl PL, Borgström E, Picelli S, Reinius B, Sandberg R, Réu P, Talavera-Lopez C, Andersson B, Blom K, Sandberg JK, Picard F, Michaëlsson J, Frisén J. Mold JE, et al. Among authors: modolo l. Cell Rep. 2021 May 25;35(8):109174. doi: 10.1016/j.celrep.2021.109174. Cell Rep. 2021. PMID: 34038736 Free article.
Evidence for close molecular proximity between reverting and undifferentiated cells.
Zreika S, Fourneaux C, Vallin E, Modolo L, Seraphin R, Moussy A, Ventre E, Bouvier M, Ozier-Lafontaine A, Bonnaffoux A, Picard F, Gandrillon O, Gonin-Giraud S. Zreika S, et al. Among authors: modolo l. BMC Biol. 2022 Jul 6;20(1):155. doi: 10.1186/s12915-022-01363-7. BMC Biol. 2022. PMID: 35794592 Free PMC article.
Differentiation is accompanied by a progressive loss in transcriptional memory.
Fourneaux C, Racine L, Koering C, Dussurgey S, Vallin E, Moussy A, Parmentier R, Brunard F, Stockholm D, Modolo L, Picard F, Gandrillon O, Paldi A, Gonin-Giraud S. Fourneaux C, et al. Among authors: modolo l. BMC Biol. 2024 Mar 12;22(1):58. doi: 10.1186/s12915-024-01846-9. BMC Biol. 2024. PMID: 38468285 Free PMC article.
TEtools facilitates big data expression analysis of transposable elements and reveals an antagonism between their activity and that of piRNA genes.
Lerat E, Fablet M, Modolo L, Lopez-Maestre H, Vieira C. Lerat E, et al. Among authors: modolo l. Nucleic Acids Res. 2017 Feb 28;45(4):e17. doi: 10.1093/nar/gkw953. Nucleic Acids Res. 2017. PMID: 28204592 Free PMC article.
This tool takes into account the TE sequence diversity of the genome, it can be applied to unannotated or unassembled genomes and is freely available under the GPL3 (https://github.com/l-modolo/TEtools). TEtools performs the mapping of RNA-seq data obtained from cla …
This tool takes into account the TE sequence diversity of the genome, it can be applied to unannotated or unassembled genomes and is freely …
Interplay between coding and exonic splicing regulatory sequences.
Fontrodona N, Aubé F, Claude JB, Polvèche H, Lemaire S, Tranchevent LC, Modolo L, Mortreux F, Bourgeois CF, Auboeuf D. Fontrodona N, et al. Among authors: modolo l. Genome Res. 2019 May;29(5):711-722. doi: 10.1101/gr.241315.118. Epub 2019 Apr 8. Genome Res. 2019. PMID: 30962178 Free PMC article.
79 results