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Page 1
Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects.
Christakos S, Dhawan P, Verstuyf A, Verlinden L, Carmeliet G. Christakos S, et al. Physiol Rev. 2016 Jan;96(1):365-408. doi: 10.1152/physrev.00014.2015. Physiol Rev. 2016. PMID: 26681795 Free PMC article. Review.
1,25-Dihydroxvitamin D3 [1,25(OH)2D3] is the hormonally active form of vitamin D. The genomic mechanism of 1,25(OH)2D3 action involves the direct binding of the 1,25(OH)2D3 activated vitamin D receptor/retinoic X receptor (VDR/RXR) hetero …
1,25-Dihydroxvitamin D3 [1,25(OH)2D3] is the hormonally active form of vitamin D. The genomic mechanism of 1,25(OH)2D3 …
Vitamin D: Production, Metabolism and Mechanisms of Action.
Bikle DD. Bikle DD. 2021 Dec 31. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. 2021 Dec 31. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 25905172 Free Books & Documents. Review.
Vitamin D production in the skin under the influence of sunlight (UVB) is maximized at levels of sunlight exposure that do not burn the skin. ...Analogs of 1,25(OH)2D are being developed to achieve specificity for non-skeletal target tissues such as the parathyroid …
Vitamin D production in the skin under the influence of sunlight (UVB) is maximized at levels of sunlight exposure that do not …
Molecular basis of vitamin D action in inflammatory bowel disease.
Triantos C, Aggeletopoulou I, Mantzaris GJ, Mouzaki A. Triantos C, et al. Autoimmun Rev. 2022 Aug;21(8):103136. doi: 10.1016/j.autrev.2022.103136. Epub 2022 Jul 2. Autoimmun Rev. 2022. PMID: 35792343 Review.
There is growing evidence of vitamin D involvement in immune regulation and gut barrier function, suggesting that vitamin D may play a critical role in the development of inflammatory bowel disease (IBD). This review presents advances in the molecul …
There is growing evidence of vitamin D involvement in immune regulation and gut barrier function, suggesting that vitamin …
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows.
Giustina A, Bilezikian JP, Adler RA, Banfi G, Bikle DD, Binkley NC, Bollerslev J, Bouillon R, Brandi ML, Casanueva FF, di Filippo L, Donini LM, Ebeling PR, Fuleihan GE, Fassio A, Frara S, Jones G, Marcocci C, Martineau AR, Minisola S, Napoli N, Procopio M, Rizzoli R, Schafer AL, Sempos CT, Ulivieri FM, Virtanen JK. Giustina A, et al. Endocr Rev. 2024 Sep 12;45(5):625-654. doi: 10.1210/endrev/bnae009. Endocr Rev. 2024. PMID: 38676447 Free PMC article.
The 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitamin D metabolism, assessment, actions, and supplementation. Novel insights into vitamin D mechanisms o …
The 6th International Conference, "Controversies in Vitamin D," was convened to discuss controversial topics, such as vitam …
The Molecular Mechanisms by Which Vitamin D Prevents Insulin Resistance and Associated Disorders.
Szymczak-Pajor I, Drzewoski J, Śliwińska A. Szymczak-Pajor I, et al. Int J Mol Sci. 2020 Sep 11;21(18):6644. doi: 10.3390/ijms21186644. Int J Mol Sci. 2020. PMID: 32932777 Free PMC article. Review.
The goal of this communication is to review the molecular mechanism by which vitamin D reduces insulin resistance and related complications. ...Appealingly, vitamin D reduces inflammation and regulates Ca(2+) level in many cell types. The …
The goal of this communication is to review the molecular mechanism by which vitamin D reduces insulin resistanc …
Mechanisms of vitamin D on skeletal muscle function: oxidative stress, energy metabolism and anabolic state.
Dzik KP, Kaczor JJ. Dzik KP, et al. Eur J Appl Physiol. 2019 Apr;119(4):825-839. doi: 10.1007/s00421-019-04104-x. Epub 2019 Mar 4. Eur J Appl Physiol. 2019. PMID: 30830277 Free PMC article. Review.
It focuses on several aspects related to cellular and molecular physiology such as VDR as the trigger point of vitamin D action, oxidative stress as a consequence of vitamin D deficiency. ...These deleterious consequences on muscle may be …
It focuses on several aspects related to cellular and molecular physiology such as VDR as the trigger point of vitamin D …
Analysis of Association between Vitamin D Deficiency and Insulin Resistance.
Szymczak-Pajor I, Śliwińska A. Szymczak-Pajor I, et al. Nutrients. 2019 Apr 6;11(4):794. doi: 10.3390/nu11040794. Nutrients. 2019. PMID: 30959886 Free PMC article. Review.
This review aims to provide molecular mechanisms showing how vitamin D deficiency may be involved in the insulin resistance formation. ...Both genomic and non-genomic action of vitamin D is directed towards insulin signaling. There …
This review aims to provide molecular mechanisms showing how vitamin D deficiency may be involved in the insulin …
Molecular Mechanisms of Vitamin D-Mediated Immunomodulation.
Khashim Alswailmi F, Shah SIA, Nawaz H, Al-Mazaideh GM. Khashim Alswailmi F, et al. Galen Med J. 2021 Jun 5;10:e2097. doi: 10.31661/gmj.v10i0.2097. eCollection 2021. Galen Med J. 2021. PMID: 35572849 Free PMC article.
Ever since discovering the fat-soluble secosteroid vitamin D, an abundance of research has been conducted on the molecular mechanisms for the multiple health benefits of this nutrient. ...Recent work has yielded important mechanistic insights into the …
Ever since discovering the fat-soluble secosteroid vitamin D, an abundance of research has been conducted on the molecular …
Mechanisms of vitamin D action in skeletal muscle.
Montenegro KR, Cruzat V, Carlessi R, Newsholme P. Montenegro KR, et al. Nutr Res Rev. 2019 Dec;32(2):192-204. doi: 10.1017/S0954422419000064. Epub 2019 Jun 17. Nutr Res Rev. 2019. PMID: 31203824 Review.
The main purpose of the present review is to describe the molecular role of vitamin D in skeletal muscle tissue function and metabolism, specifically in relation to proliferation, differentiation and protein synthesis processes. In addition, the present revie …
The main purpose of the present review is to describe the molecular role of vitamin D in skeletal muscle tissue functio …
Molecular mechanisms of vitamin D action.
Haussler MR, Whitfield GK, Kaneko I, Haussler CA, Hsieh D, Hsieh JC, Jurutka PW. Haussler MR, et al. Calcif Tissue Int. 2013 Feb;92(2):77-98. doi: 10.1007/s00223-012-9619-0. Epub 2012 Jul 11. Calcif Tissue Int. 2013. PMID: 22782502 Review.
The hormonal metabolite of vitamin D, 1alpha,25-dihydroxyvitamin D(3) (1,25D), initiates biological responses via binding to the vitamin D receptor (VDR). ...Thus, vitamin D action in a particular cell depends upon the metabolic pr …
The hormonal metabolite of vitamin D, 1alpha,25-dihydroxyvitamin D(3) (1,25D), initiates biological responses via binding to t …
600 results