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Trispecific antibodies for CD16A-directed NK cell engagement and dual-targeting of tumor cells.
Protein Eng Des Sel. 2017 Sep 1;30(9):673-684. doi: 10.1093/protein/gzx043.
Protein Eng Des Sel. 2017.
PMID: 28981915
A tetravalent bispecific TandAb (CD19/CD3), AFM11, efficiently recruits T cells for the potent lysis of CD19(+) tumor cells.
Reusch U, Duell J, Ellwanger K, Herbrecht C, Knackmuss SH, Fucek I, Eser M, McAleese F, Molkenthin V, Gall FL, Topp M, Little M, Zhukovsky EA.
Reusch U, et al. Among authors: molkenthin v.
MAbs. 2015;7(3):584-604. doi: 10.1080/19420862.2015.1029216.
MAbs. 2015.
PMID: 25875246
Free PMC article.
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Highly Specific and Effective Targeting of EGFRvIII-Positive Tumors with TandAb Antibodies.
Ellwanger K, Reusch U, Fucek I, Knackmuss S, Weichel M, Gantke T, Molkenthin V, Zhukovsky EA, Tesar M, Treder M.
Ellwanger K, et al. Among authors: molkenthin v.
Front Oncol. 2017 May 19;7:100. doi: 10.3389/fonc.2017.00100. eCollection 2017.
Front Oncol. 2017.
PMID: 28596941
Free PMC article.
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