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Adaptive immune cells are necessary for SARS-CoV-2-induced pathology.
Imbiakha B, Sahler JM, Buchholz DW, Ezzatpour S, Jager M, Choi A, Monreal IA, Byun H, Adeleke RA, Leach J, Whittaker G, Dewhurst S, Rudd BD, Aguilar HC, August A. Imbiakha B, et al. Among authors: monreal ia. Sci Adv. 2024 Jan 5;10(1):eadg5461. doi: 10.1126/sciadv.adg5461. Epub 2024 Jan 3. Sci Adv. 2024. PMID: 38170764 Free PMC article.
Thermophobic Trehalose Glycopolymers as Smart C-Type Lectin Receptor Vaccine Adjuvants.
Hendricksen AT, Ezzatpour S, Pulukuri AJ, Ryan AT, Flanagan TJ, Frantz W, Buchholz DW, Ortega V, Monreal IA, Sahler JM, Nielsen AE, Aguilar HC, Mancini RJ. Hendricksen AT, et al. Among authors: monreal ia. Adv Healthc Mater. 2023 Jul;12(19):e2202918. doi: 10.1002/adhm.202202918. Epub 2023 Apr 25. Adv Healthc Mater. 2023. PMID: 37002787
Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection.
Tang AT, Buchholz DW, Szigety KM, Imbiakha B, Gao S, Frankfurter M, Wang M, Yang J, Hewins P, Mericko-Ishizuka P, Leu NA, Sterling S, Monreal IA, Sahler J, August A, Zhu X, Jurado KA, Xu M, Morrisey EE, Millar SE, Aguilar HC, Kahn ML. Tang AT, et al. Among authors: monreal ia. PLoS Biol. 2023 Feb 6;21(2):e3001989. doi: 10.1371/journal.pbio.3001989. eCollection 2023 Feb. PLoS Biol. 2023. PMID: 36745682 Free PMC article.
Multivalent viral particles elicit safe and efficient immunoprotection against Nipah Hendra and Ebola viruses.
Ithinji DG, Buchholz DW, Ezzatpour S, Monreal IA, Cong Y, Sahler J, Bangar AS, Imbiakha B, Upadhye V, Liang J, Ma A, Bradel-Tretheway B, Kaza B, Yeo YY, Choi EJ, Johnston GP, Huzella L, Kollins E, Dixit S, Yu S, Postnikova E, Ortega V, August A, Holbrook MR, Aguilar HC. Ithinji DG, et al. Among authors: monreal ia. NPJ Vaccines. 2022 Dec 17;7(1):166. doi: 10.1038/s41541-022-00588-5. NPJ Vaccines. 2022. PMID: 36528644 Free PMC article.
A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic.
Shapira T, Monreal IA, Dion SP, Buchholz DW, Imbiakha B, Olmstead AD, Jager M, Désilets A, Gao G, Martins M, Vandal T, Thompson CAH, Chin A, Rees WD, Steiner T, Nabi IR, Marsault E, Sahler J, Diel DG, Van de Walle GR, August A, Whittaker GR, Boudreault PL, Leduc R, Aguilar HC, Jean F. Shapira T, et al. Among authors: monreal ia. Nature. 2022 May;605(7909):340-348. doi: 10.1038/s41586-022-04661-w. Epub 2022 Mar 28. Nature. 2022. PMID: 35344983 Free PMC article.
SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice.
Tang AT, Buchholz DW, Szigety KM, Imbhiaka B, Gao S, Frankfurter M, Wang M, Yang J, Hewins P, Mericko-Ishizuka P, Adrian Leu N, Sterling S, Monreal IA, Sahler J, August A, Zhu X, Jurado KA, Xu M, Morrisey EE, Millar SE, Aguilar HC, Kahn ML. Tang AT, et al. Among authors: monreal ia. bioRxiv [Preprint]. 2021 Dec 7:2021.12.04.471245. doi: 10.1101/2021.12.04.471245. bioRxiv. 2021. PMID: 34909769 Free PMC article. Preprint.
Antivirals targeting paramyxovirus membrane fusion.
Contreras EM, Monreal IA, Ruvalcaba M, Ortega V, Aguilar HC. Contreras EM, et al. Among authors: monreal ia. Curr Opin Virol. 2021 Dec;51:34-47. doi: 10.1016/j.coviro.2021.09.003. Epub 2021 Sep 27. Curr Opin Virol. 2021. PMID: 34592709 Free PMC article. Review.
23 results