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AI-based histologic scoring enables automated and reproducible assessment of enrollment criteria and endpoints in NASH clinical trials.
Iyer JS, Pokkalla H, Biddle-Snead C, Carrasco-Zevallos O, Lin M, Shanis Z, Le Q, Juyal D, Pouryahya M, Pedawi A, Hoffman S, Elliott H, Leidal K, Myers RP, Chung C, Billin AN, Watkins TR, Resnick M, Wack K, Glickman J, Burt AD, Loomba R, Sanyal AJ, Montalto MC, Beck AH, Taylor-Weiner A, Wapinski I. Iyer JS, et al. Among authors: montalto mc. medRxiv [Preprint]. 2023 Apr 25:2023.04.20.23288534. doi: 10.1101/2023.04.20.23288534. medRxiv. 2023. PMID: 37162870 Free PMC article. Preprint.
Integration of deep learning-based histopathology and transcriptomics reveals key genes associated with fibrogenesis in patients with advanced NASH.
Conway J, Pouryahya M, Gindin Y, Pan DZ, Carrasco-Zevallos OM, Mountain V, Subramanian GM, Montalto MC, Resnick M, Beck AH, Huss RS, Myers RP, Taylor-Weiner A, Wapinski I, Chung C. Conway J, et al. Among authors: montalto mc. Cell Rep Med. 2023 Apr 18;4(4):101016. doi: 10.1016/j.xcrm.2023.101016. Cell Rep Med. 2023. PMID: 37075704 Free PMC article.
Human-interpretable image features derived from densely mapped cancer pathology slides predict diverse molecular phenotypes.
Diao JA, Wang JK, Chui WF, Mountain V, Gullapally SC, Srinivasan R, Mitchell RN, Glass B, Hoffman S, Rao SK, Maheshwari C, Lahiri A, Prakash A, McLoughlin R, Kerner JK, Resnick MB, Montalto MC, Khosla A, Wapinski IN, Beck AH, Elliott HL, Taylor-Weiner A. Diao JA, et al. Among authors: montalto mc. Nat Commun. 2021 Mar 12;12(1):1613. doi: 10.1038/s41467-021-21896-9. Nat Commun. 2021. PMID: 33712588 Free PMC article.
A Machine Learning Approach Enables Quantitative Measurement of Liver Histology and Disease Monitoring in NASH.
Taylor-Weiner A, Pokkalla H, Han L, Jia C, Huss R, Chung C, Elliott H, Glass B, Pethia K, Carrasco-Zevallos O, Shukla C, Khettry U, Najarian R, Taliano R, Subramanian GM, Myers RP, Wapinski I, Khosla A, Resnick M, Montalto MC, Anstee QM, Wong VW, Trauner M, Lawitz EJ, Harrison SA, Okanoue T, Romero-Gomez M, Goodman Z, Loomba R, Beck AH, Younossi ZM. Taylor-Weiner A, et al. Among authors: montalto mc. Hepatology. 2021 Jul;74(1):133-147. doi: 10.1002/hep.31750. Epub 2021 Jun 24. Hepatology. 2021. PMID: 33570776 Free PMC article.
30 results