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Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels.
Gribkoff VK, Starrett JE Jr, Dworetzky SI, Hewawasam P, Boissard CG, Cook DA, Frantz SW, Heman K, Hibbard JR, Huston K, Johnson G, Krishnan BS, Kinney GG, Lombardo LA, Meanwell NA, Molinoff PB, Myers RA, Moon SL, Ortiz A, Pajor L, Pieschl RL, Post-Munson DJ, Signor LJ, Srinivas N, Taber MT, Thalody G, Trojnacki JT, Wiener H, Yeleswaram K, Yeola SW. Gribkoff VK, et al. Among authors: moon sl. Nat Med. 2001 Apr;7(4):471-7. doi: 10.1038/86546. Nat Med. 2001. PMID: 11283675
3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: opener of large-conductance Ca(2+)-activated potassium (maxi-K) channels, identification, solubility, and SAR.
Romine JL, Martin SW, Meanwell NA, Gribkoff VK, Boissard CG, Dworetzky SI, Natale J, Moon S, Ortiz A, Yeleswaram S, Pajor L, Gao Q, Starrett JE Jr. Romine JL, et al. J Med Chem. 2007 Feb 8;50(3):528-42. doi: 10.1021/jm061006n. J Med Chem. 2007. PMID: 17266205
The synthesis and structure-activity relationships of 4-aryl-3-aminoquinolin-2-ones: a new class of calcium-dependent, large conductance, potassium (maxi-K) channel openers targeted for post-stroke neuroprotection.
Hewawasam P, Fan W, Knipe J, Moon SL, Boissard CG, Gribkoff VK, Starrett JE. Hewawasam P, et al. Among authors: moon sl. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1779-83. doi: 10.1016/s0960-894x(02)00240-8. Bioorg Med Chem Lett. 2002. PMID: 12067560
A role for sigma binding in the antipsychotic profile of BMY 14802?
Taylor DP, Eison MS, Moon SL, Schlemmer RF Jr, Shukla UA, VanderMaelen CP, Yocca FD, Gallant DJ, Behling SH, Boissard CG, et al. Taylor DP, et al. Among authors: moon sl. NIDA Res Monogr. 1993;133:125-57. NIDA Res Monogr. 1993. PMID: 8232511 Review.
Translation feedback control in the brain.
Moon SL. Moon SL. Nat Rev Mol Cell Biol. 2024 May 2. doi: 10.1038/s41580-024-00741-z. Online ahead of print. Nat Rev Mol Cell Biol. 2024. PMID: 38698077 No abstract available.
32 results