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Page 1
Discovery of tertiary sulfonamides as potent liver X receptor antagonists.
Zuercher WJ, Buckholz RG, Campobasso N, Collins JL, Galardi CM, Gampe RT, Hyatt SM, Merrihew SL, Moore JT, Oplinger JA, Reid PR, Spearing PK, Stanley TB, Stewart EL, Willson TM. Zuercher WJ, et al. Among authors: moore jt. J Med Chem. 2010 Apr 22;53(8):3412-6. doi: 10.1021/jm901797p. J Med Chem. 2010. PMID: 20345102
A new series of estrogen receptor modulators that display selectivity for estrogen receptor beta.
Henke BR, Consler TG, Go N, Hale RL, Hohman DR, Jones SA, Lu AT, Moore LB, Moore JT, Orband-Miller LA, Robinett RG, Shearin J, Spearing PK, Stewart EL, Turnbull PS, Weaver SL, Williams SP, Wisely GB, Lambert MH. Henke BR, et al. Among authors: moore lb, moore jt. J Med Chem. 2002 Dec 5;45(25):5492-505. doi: 10.1021/jm020291h. J Med Chem. 2002. PMID: 12459017
The nuclear receptor superfamily and drug discovery.
Moore JT, Collins JL, Pearce KH. Moore JT, et al. ChemMedChem. 2006 May;1(5):504-23. doi: 10.1002/cmdc.200600006. ChemMedChem. 2006. PMID: 16892386 Review. No abstract available.
Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.
Spencer TA, Li D, Russel JS, Collins JL, Bledsoe RK, Consler TG, Moore LB, Galardi CM, McKee DD, Moore JT, Watson MA, Parks DJ, Lambert MH, Willson TM. Spencer TA, et al. Among authors: moore lb, moore jt. J Med Chem. 2001 Mar 15;44(6):886-97. doi: 10.1021/jm0004749. J Med Chem. 2001. PMID: 11300870
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors.
Xu HE, Lambert MH, Montana VG, Plunket KD, Moore LB, Collins JL, Oplinger JA, Kliewer SA, Gampe RT Jr, McKee DD, Moore JT, Willson TM. Xu HE, et al. Among authors: moore lb, moore jt. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13919-24. doi: 10.1073/pnas.241410198. Epub 2001 Nov 6. Proc Natl Acad Sci U S A. 2001. PMID: 11698662 Free PMC article.
222 results