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Pre-mRNA splicing: awash in a sea of proteins.
Jurica MS, Moore MJ. Jurica MS, et al. Among authors: moore mj. Mol Cell. 2003 Jul;12(1):5-14. doi: 10.1016/s1097-2765(03)00270-3. Mol Cell. 2003. PMID: 12887888 Review.
Single molecule analysis reveals reversible and irreversible steps during spliceosome activation.
Hoskins AA, Rodgers ML, Friedman LJ, Gelles J, Moore MJ. Hoskins AA, et al. Among authors: moore mj. Elife. 2016 May 31;5:e14166. doi: 10.7554/eLife.14166. Elife. 2016. PMID: 27244240 Free PMC article.
A convergence of rRNA and mRNA quality control pathways revealed by mechanistic analysis of nonfunctional rRNA decay.
Cole SE, LaRiviere FJ, Merrikh CN, Moore MJ. Cole SE, et al. Among authors: moore mj. Mol Cell. 2009 May 14;34(4):440-50. doi: 10.1016/j.molcel.2009.04.017. Mol Cell. 2009. PMID: 19481524 Free PMC article.
Pre-mRNA processing reaches back to transcription and ahead to translation.
Moore MJ, Proudfoot NJ. Moore MJ, et al. Cell. 2009 Feb 20;136(4):688-700. doi: 10.1016/j.cell.2009.02.001. Cell. 2009. PMID: 19239889 Review.
Association of ribosomal proteins with nascent transcripts in S. cerevisiae.
Schroder PA, Moore MJ. Schroder PA, et al. Among authors: moore mj. RNA. 2005 Oct;11(10):1521-9. doi: 10.1261/rna.2134305. RNA. 2005. PMID: 16199762 Free PMC article.
Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.
Tange TØ, Shibuya T, Jurica MS, Moore MJ. Tange TØ, et al. Among authors: moore mj. RNA. 2005 Dec;11(12):1869-83. doi: 10.1261/rna.2155905. RNA. 2005. PMID: 16314458 Free PMC article.
The spliceosome: a flexible, reversible macromolecular machine.
Hoskins AA, Moore MJ. Hoskins AA, et al. Among authors: moore mj. Trends Biochem Sci. 2012 May;37(5):179-88. doi: 10.1016/j.tibs.2012.02.009. Epub 2012 Apr 3. Trends Biochem Sci. 2012. PMID: 22480731 Free PMC article. Review.
The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.
Singh G, Kucukural A, Cenik C, Leszyk JD, Shaffer SA, Weng Z, Moore MJ. Singh G, et al. Among authors: moore mj. Cell. 2012 Nov 9;151(4):750-764. doi: 10.1016/j.cell.2012.10.007. Epub 2012 Oct 18. Cell. 2012. PMID: 23084401 Free PMC article.
Ordered and dynamic assembly of single spliceosomes.
Hoskins AA, Friedman LJ, Gallagher SS, Crawford DJ, Anderson EG, Wombacher R, Ramirez N, Cornish VW, Gelles J, Moore MJ. Hoskins AA, et al. Among authors: moore mj. Science. 2011 Mar 11;331(6022):1289-95. doi: 10.1126/science.1198830. Science. 2011. PMID: 21393538 Free PMC article.
The biflavonoid isoginkgetin is a general inhibitor of Pre-mRNA splicing.
O'Brien K, Matlin AJ, Lowell AM, Moore MJ. O'Brien K, et al. Among authors: moore mj. J Biol Chem. 2008 Nov 28;283(48):33147-54. doi: 10.1074/jbc.M805556200. Epub 2008 Sep 30. J Biol Chem. 2008. PMID: 18826947 Free PMC article.
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