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Energy metabolism in uncoupling protein 3 gene knockout mice.
Vidal-Puig AJ, Grujic D, Zhang CY, Hagen T, Boss O, Ido Y, Szczepanik A, Wade J, Mootha V, Cortright R, Muoio DM, Lowell BB. Vidal-Puig AJ, et al. J Biol Chem. 2000 May 26;275(21):16258-66. doi: 10.1074/jbc.M910179199. J Biol Chem. 2000. PMID: 10748196
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.
Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC. Mootha VK, et al. Nat Genet. 2003 Jul;34(3):267-73. doi: 10.1038/ng1180. Nat Genet. 2003. PMID: 12808457
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle.
Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, Sihag S, Yang W, Altshuler D, Puigserver P, Patterson N, Willy PJ, Schulman IG, Heyman RA, Lander ES, Spiegelman BM. Mootha VK, et al. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6570-5. doi: 10.1073/pnas.0401401101. Epub 2004 Apr 20. Proc Natl Acad Sci U S A. 2004. PMID: 15100410 Free PMC article.
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.
Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY, Mootha VK, Jäger S, Vianna CR, Reznick RM, Cui L, Manieri M, Donovan MX, Wu Z, Cooper MP, Fan MC, Rohas LM, Zavacki AM, Cinti S, Shulman GI, Lowell BB, Krainc D, Spiegelman BM. Lin J, et al. Among authors: mootha vk. Cell. 2004 Oct 1;119(1):121-35. doi: 10.1016/j.cell.2004.09.013. Cell. 2004. PMID: 15454086
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