Mootha VK - Search Results

1

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.

Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P. Cunningham JT, et al. Among authors: mootha vk. Nature. 2007 Nov 29;450(7170):736-40. doi: 10.1038/nature06322. Nature. 2007. PMID: 18046414

2

Assessment of uncoupling activity of uncoupling protein 3 using a yeast heterologous expression system.

Zhang CY, Hagen T, Mootha VK, Slieker LJ, Lowell BB. Zhang CY, et al. Among authors: mootha vk. FEBS Lett. 1999 Apr 23;449(2-3):129-34. doi: 10.1016/s0014-5793(99)00441-x. FEBS Lett. 1999. PMID: 10338118

3

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1.

Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, Spiegelman BM. Wu Z, et al. Cell. 1999 Jul 9;98(1):115-24. doi: 10.1016/S0092-8674(00)80611-X. Cell. 1999. PMID: 10412986

4

Energy metabolism in uncoupling protein 3 gene knockout mice.

Vidal-Puig AJ, Grujic D, Zhang CY, Hagen T, Boss O, Ido Y, Szczepanik A, Wade J, Mootha V, Cortright R, Muoio DM, Lowell BB. Vidal-Puig AJ, et al. J Biol Chem. 2000 May 26;275(21):16258-66. doi: 10.1074/jbc.M910179199. J Biol Chem. 2000. PMID: 10748196

5

A reversible component of mitochondrial respiratory dysfunction in apoptosis can be rescued by exogenous cytochrome c.

Mootha VK, Wei MC, Buttle KF, Scorrano L, Panoutsakopoulou V, Mannella CA, Korsmeyer SJ. Mootha VK, et al. EMBO J. 2001 Feb 15;20(4):661-71. doi: 10.1093/emboj/20.4.661. EMBO J. 2001. PMID: 11179211 Free PMC article.

6

Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1.

Puigserver P, Rhee J, Lin J, Wu Z, Yoon JC, Zhang CY, Krauss S, Mootha VK, Lowell BB, Spiegelman BM. Puigserver P, et al. Among authors: mootha vk. Mol Cell. 2001 Nov;8(5):971-82. doi: 10.1016/s1097-2765(01)00390-2. Mol Cell. 2001. PMID: 11741533

7

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC. Mootha VK, et al. Nat Genet. 2003 Jul;34(3):267-73. doi: 10.1038/ng1180. Nat Genet. 2003. PMID: 12808457

8

Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle.

Mootha VK, Handschin C, Arlow D, Xie X, St Pierre J, Sihag S, Yang W, Altshuler D, Puigserver P, Patterson N, Willy PJ, Schulman IG, Heyman RA, Lander ES, Spiegelman BM. Mootha VK, et al. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6570-5. doi: 10.1073/pnas.0401401101. Epub 2004 Apr 20. Proc Natl Acad Sci U S A. 2004. PMID: 15100410 Free PMC article.

9

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.

Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY, Mootha VK, Jäger S, Vianna CR, Reznick RM, Cui L, Manieri M, Donovan MX, Wu Z, Cooper MP, Fan MC, Rohas LM, Zavacki AM, Cinti S, Shulman GI, Lowell BB, Krainc D, Spiegelman BM. Lin J, et al. Among authors: mootha vk. Cell. 2004 Oct 1;119(1):121-35. doi: 10.1016/j.cell.2004.09.013. Cell. 2004. PMID: 15454086

10

Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals.

Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. Xie X, et al. Nature. 2005 Mar 17;434(7031):338-45. doi: 10.1038/nature03441. Epub 2005 Feb 27. Nature. 2005. PMID: 15735639 Free PMC article.

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