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Pulmonary BCG induces lung-resident macrophage activation and confers long-term protection against tuberculosis.
Mata E, Tarancon R, Guerrero C, Moreo E, Moreau F, Uranga S, Gomez AB, Marinova D, Domenech M, Gonzalez-Camacho F, Monzon M, Badiola J, Dominguez-Andres J, Yuste J, Anel A, Peixoto A, Martin C, Aguilo N. Mata E, et al. Among authors: moreau f. Sci Immunol. 2021 Sep 24;6(63):eabc2934. doi: 10.1126/sciimmunol.abc2934. Epub 2021 Sep 24. Sci Immunol. 2021. PMID: 34559551
Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli.
Allen AC, Malaga W, Gaudin C, Volle A, Moreau F, Hassan A, Astarie-Dequeker C, Peixoto A, Antoine R, Pawlik A, Frigui W, Berrone C, Brosch R, Supply P, Guilhot C. Allen AC, et al. Among authors: moreau f. Nat Microbiol. 2021 Aug;6(8):1082-1093. doi: 10.1038/s41564-021-00938-4. Epub 2021 Jul 22. Nat Microbiol. 2021. PMID: 34294904 Free article.
Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli.
Malaga W, Payros D, Meunier E, Frigui W, Sayes F, Pawlik A, Orgeur M, Berrone C, Moreau F, Mazères S, Gonzalo-Asensio J, Rengel D, Martin C, Astarie-Dequeker C, Mourey L, Brosch R, Guilhot C. Malaga W, et al. Among authors: moreau f. PLoS Pathog. 2023 Jul 14;19(7):e1011437. doi: 10.1371/journal.ppat.1011437. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37450466 Free PMC article.
Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages.
Payros D, Alonso H, Malaga W, Volle A, Mazères S, Déjean S, Valière S, Moreau F, Balor S, Stella A, Combes-Soia L, Burlet-Schiltz O, Bouchez O, Nigou J, Astarie-Dequeker C, Guilhot C. Payros D, et al. Among authors: moreau f. PLoS Pathog. 2021 Nov 1;17(11):e1010020. doi: 10.1371/journal.ppat.1010020. eCollection 2021 Nov. PLoS Pathog. 2021. PMID: 34724002 Free PMC article.
Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology.
Bagayoko S, Leon-Icaza SA, Pinilla M, Hessel A, Santoni K, Péricat D, Bordignon PJ, Moreau F, Eren E, Boyancé A, Naser E, Lefèvre L, Berrone C, Iakobachvili N, Metais A, Rombouts Y, Lugo-Villarino G, Coste A, Attrée I, Frank DW, Clevers H, Peters PJ, Cougoule C, Planès R, Meunier E. Bagayoko S, et al. Among authors: moreau f. PLoS Pathog. 2021 Sep 13;17(9):e1009927. doi: 10.1371/journal.ppat.1009927. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34516571 Free PMC article.
362 results