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CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia.
Bennett C, Lawrence M, Guerrero JA, Stritt S, Waller AK, Yan Y, Mifsud RW, Ballester-Beltrán J, Baig A, Mueller A, Mayer L, Warland J, Penkett CJ, Akbari P, Moreau T, Evans AL, Mookerjee S, Hoffman GJ, Saeb-Parsy K, Adams DJ, Couzens AL, Bender M, Erber WN, Nieswandt B, Read RJ, Ghevaert C. Bennett C, et al. Among authors: moreau t. Blood. 2022 Apr 7;139(14):2227-2239. doi: 10.1182/blood.2021013113. Blood. 2022. PMID: 35051265 Free PMC article.
Structurally graduated collagen scaffolds applied to the ex vivo generation of platelets from human pluripotent stem cell-derived megakaryocytes: Enhancing production and purity.
Shepherd JH, Howard D, Waller AK, Foster HR, Mueller A, Moreau T, Evans AL, Arumugam M, Bouët Chalon G, Vriend E, Davidenko N, Ghevaert C, Best SM, Cameron RE. Shepherd JH, et al. Among authors: moreau t. Biomaterials. 2018 Nov;182:135-144. doi: 10.1016/j.biomaterials.2018.08.019. Epub 2018 Aug 8. Biomaterials. 2018. PMID: 30118981
Transcription Factor Levels after Forward Programming of Human Pluripotent Stem Cells with GATA1, FLI1, and TAL1 Determine Megakaryocyte versus Erythroid Cell Fate Decision.
Dalby A, Ballester-Beltrán J, Lincetto C, Mueller A, Foad N, Evans A, Baye J, Turro E, Moreau T, Tijssen MR, Ghevaert C. Dalby A, et al. Among authors: moreau t. Stem Cell Reports. 2018 Dec 11;11(6):1462-1478. doi: 10.1016/j.stemcr.2018.11.001. Epub 2018 Nov 29. Stem Cell Reports. 2018. PMID: 30503262 Free PMC article.
Mapping the biogenesis of forward programmed megakaryocytes from induced pluripotent stem cells.
Lawrence M, Shahsavari A, Bornelöv S, Moreau T, McDonald R, Vallance TM, Kania K, Paramor M, Baye J, Perrin M, Steindel M, Jimenez-Gomez P, Penfold C, Mohorianu I, Ghevaert C. Lawrence M, et al. Among authors: moreau t. Sci Adv. 2022 Feb 18;8(7):eabj8618. doi: 10.1126/sciadv.abj8618. Epub 2022 Feb 16. Sci Adv. 2022. PMID: 35171685 Free PMC article.
Brain-derived Neurotrophic Factor in Megakaryocytes.
Chacón-Fernández P, Säuberli K, Colzani M, Moreau T, Ghevaert C, Barde YA. Chacón-Fernández P, et al. Among authors: moreau t. J Biol Chem. 2016 May 6;291(19):9872-81. doi: 10.1074/jbc.M116.720029. Epub 2016 Mar 22. J Biol Chem. 2016. PMID: 27006395 Free PMC article.
Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming.
Moreau T, Evans AL, Vasquez L, Tijssen MR, Yan Y, Trotter MW, Howard D, Colzani M, Arumugam M, Wu WH, Dalby A, Lampela R, Bouet G, Hobbs CM, Pask DC, Payne H, Ponomaryov T, Brill A, Soranzo N, Ouwehand WH, Pedersen RA, Ghevaert C. Moreau T, et al. Nat Commun. 2016 Apr 7;7:11208. doi: 10.1038/ncomms11208. Nat Commun. 2016. PMID: 27052461 Free PMC article.
Inhibition of profibrotic microRNA-21 affects platelets and their releasate.
Barwari T, Eminaga S, Mayr U, Lu R, Armstrong PC, Chan MV, Sahraei M, Fernández-Fuertes M, Moreau T, Barallobre-Barreiro J, Lynch M, Yin X, Schulte C, Baig F, Pechlaner R, Langley SR, Zampetaki A, Santer P, Weger M, Plasenzotti R, Schosserer M, Grillari J, Kiechl S, Willeit J, Shah AM, Ghevaert C, Warner TD, Fernández-Hernando C, Suárez Y, Mayr M. Barwari T, et al. Among authors: moreau t. JCI Insight. 2018 Nov 2;3(21):e123335. doi: 10.1172/jci.insight.123335. JCI Insight. 2018. PMID: 30385722 Free PMC article.
500 results