Morrice N - Search Results

1

Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivo.

Lizcano JM, Deak M, Morrice N, Kieloch A, Hastie CJ, Dong L, Schutkowski M, Reimer U, Alessi DR. Lizcano JM, et al. Among authors: morrice n. J Biol Chem. 2002 Aug 2;277(31):27839-49. doi: 10.1074/jbc.M202042200. Epub 2002 May 22. J Biol Chem. 2002. PMID: 12023960 Free article.

2

Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.

Jaleel M, McBride A, Lizcano JM, Deak M, Toth R, Morrice NA, Alessi DR. Jaleel M, et al. FEBS Lett. 2005 Feb 28;579(6):1417-23. doi: 10.1016/j.febslet.2005.01.042. FEBS Lett. 2005. PMID: 15733851 Free article.

3

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases.

Vitari AC, Deak M, Morrice NA, Alessi DR. Vitari AC, et al. Biochem J. 2005 Oct 1;391(Pt 1):17-24. doi: 10.1042/BJ20051180. Biochem J. 2005. PMID: 16083423 Free PMC article.

4

WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate.

Vitari AC, Deak M, Collins BJ, Morrice N, Prescott AR, Phelan A, Humphreys S, Alessi DR. Vitari AC, et al. Among authors: morrice n. Biochem J. 2004 Feb 15;378(Pt 1):257-68. doi: 10.1042/BJ20031692. Biochem J. 2004. PMID: 14611643 Free PMC article.

5

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.

Sapkota GP, Boudeau J, Deak M, Kieloch A, Morrice N, Alessi DR. Sapkota GP, et al. Among authors: morrice n. Biochem J. 2002 Mar 1;362(Pt 2):481-90. doi: 10.1042/0264-6021:3620481. Biochem J. 2002. PMID: 11853558 Free PMC article.

6

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo.

Casamayor A, Morrice NA, Alessi DR. Casamayor A, et al. Among authors: morrice na. Biochem J. 1999 Sep 1;342 ( Pt 2)(Pt 2):287-92. Biochem J. 1999. PMID: 10455013 Free PMC article.

7

Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase.

Kobayashi T, Deak M, Morrice N, Cohen P. Kobayashi T, et al. Among authors: morrice n. Biochem J. 1999 Nov 15;344 Pt 1(Pt 1):189-97. Biochem J. 1999. PMID: 10548550 Free PMC article.

8

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth.

Sapkota GP, Kieloch A, Lizcano JM, Lain S, Arthur JS, Williams MR, Morrice N, Deak M, Alessi DR. Sapkota GP, et al. Among authors: morrice n. J Biol Chem. 2001 Jun 1;276(22):19469-82. doi: 10.1074/jbc.M009953200. Epub 2001 Jan 31. J Biol Chem. 2001. PMID: 11297520 Free article.

9

Characterisation of the sites of DNA damage-induced 53BP1 phosphorylation catalysed by ATM and ATR.

Jowsey P, Morrice NA, Hastie CJ, McLauchlan H, Toth R, Rouse J. Jowsey P, et al. DNA Repair (Amst). 2007 Oct 1;6(10):1536-44. doi: 10.1016/j.dnarep.2007.04.011. Epub 2007 Jun 5. DNA Repair (Amst). 2007. PMID: 17553757

10

Novel procedure to investigate the effect of phosphorylation on protein complex formation in vitro and in cells.

Rembutsu M, Soutar MP, Van Aalten L, Gourlay R, Hastie CJ, McLauchlan H, Morrice NA, Cole AR, Sutherland C. Rembutsu M, et al. Biochemistry. 2008 Feb 19;47(7):2153-61. doi: 10.1021/bi702030w. Epub 2008 Jan 26. Biochemistry. 2008. PMID: 18220421

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