Morrissette MM - Search Results

1

Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 4. Addition of chromone moiety enhances leukotriene D4 receptor binding affinity.

Huang FC, Galemmo RA Jr, Poli GB, Learn KS, Morrissette MM, Johnson WH Jr, Dankulich WP, Campbell HF, Carnathan GW, VanInwegen RG. Huang FC, et al. Among authors: morrissette mm. J Med Chem. 1991 May;34(5):1704-7. doi: 10.1021/jm00109a025. J Med Chem. 1991. PMID: 1851845

2

4-[2-[Methyl(2-phenethyl)amino]-2-oxoethyl]-8-(phenylmethoxy)-2- naphthalenecarboxylic acid: a high affinity, competitive, orally active leukotriene B4 receptor antagonist.

Huang FC, Chan WK, Warus JD, Morrissette MM, Moriarty KJ, Chang MN, Travis JJ, Mitchell LS, Nuss GW, Sutherland CA. Huang FC, et al. Among authors: morrissette mm. J Med Chem. 1992 Oct 30;35(22):4253-5. doi: 10.1021/jm00100a034. J Med Chem. 1992. PMID: 1331462 No abstract available.

3

Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 2. Effects of an additional phenyl ring on receptor affinity.

Huang FC, Galemmo RA Jr, Johnson WH Jr, Poli GB, Morrissette MM, Mencel JJ, Warus JD, Campbell HF, Nuss GW, Carnathan GW, et al. Huang FC, et al. Among authors: morrissette mm. J Med Chem. 1990 Apr;33(4):1194-200. doi: 10.1021/jm00166a017. J Med Chem. 1990. PMID: 2157010

4

A novel series of [2-[methyl(2-phenethyl)amino]-2-oxoethyl] benzene-containing leukotriene B4 antagonists: initial structure-activity relationships.

Huang FC, Chan WK, Moriarty KJ, Poli G, Morrissette MM, Galemmo RA, Warus JD, Dankulich WP, Sutherland CA. Huang FC, et al. Among authors: morrissette mm. J Med Chem. 1996 Sep 13;39(19):3748-55. doi: 10.1021/jm9506985. J Med Chem. 1996. PMID: 8809163

5

Structure-activity relationships study of two series of leukotriene B4 antagonists: novel indolyl and naphthyl compounds substituted with a 2-[methyl(2-phenethyl)amino]-2-oxoethyl side chain.

Chan WK, Huang FC, Morrissette MM, Warus JD, Moriarty KJ, Galemmo RA, Dankulich WD, Poli G, Sutherland CA. Chan WK, et al. Among authors: morrissette mm. J Med Chem. 1996 Sep 13;39(19):3756-68. doi: 10.1021/jm950699x. J Med Chem. 1996. PMID: 8809164

6

Dual inhibition of phosphodiesterase 4 and matrix metalloproteinases by an (arylsulfonyl)hydroxamic acid template.

Groneberg RD, Burns CJ, Morrissette MM, Ullrich JW, Morris RL, Darnbrough S, Djuric SW, Condon SM, McGeehan GM, Labaudiniere R, Neuenschwander K, Scotese AC, Kline JA. Groneberg RD, et al. Among authors: morrissette mm. J Med Chem. 1999 Feb 25;42(4):541-4. doi: 10.1021/jm980567e. J Med Chem. 1999. PMID: 10052961 No abstract available.

7

Nanomolar Inhibitors for Two Distinct Biological Target Families from a Single Synthetic Sequence: A Next Step in Combinatorial Library Design?

Burns CJ, Groneberg RD, Salvino JM, McGeehan G, Condon SM, Morris R, Morrissette M, Mathew R, Darnbrough S, Neuenschwander K, Scotese A, Djuric SW, Ullrich J, Labaudiniere R. Burns CJ, et al. Angew Chem Int Ed Engl. 1998 Nov 2;37(20):2848-2850. doi: 10.1002/(SICI)1521-3773(19981102)37:20<2848::AID-ANIE2848>3.0.CO;2-C. Angew Chem Int Ed Engl. 1998. PMID: 29711099

8

Low molecular weight thrombin inhibitors with excellent potency, metabolic stability, and oral bioavailability.

Morrissette MM, Stauffer KJ, Williams PD, Lyle TA, Vacca JP, Krueger JA, Lewis SD, Lucas BJ, Wong BK, White RB, Miller-Stein C, Lyle EA, Wallace AA, Leonard YM, Welsh DC, Lynch JJ, McMasters DR. Morrissette MM, et al. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4161-4. doi: 10.1016/j.bmcl.2004.06.030. Bioorg Med Chem Lett. 2004. PMID: 15261262

9

Unexpected enhancement of thrombin inhibitor potency with o-aminoalkylbenzylamides in the P1 position.

Rittle KE, Barrow JC, Cutrona KJ, Glass KL, Krueger JA, Kuo LC, Lewis SD, Lucas BJ, McMasters DR, Morrissette MM, Nantermet PG, Newton CL, Sanders WM, Yan Y, Vacca JP, Selnick HG. Rittle KE, et al. Among authors: morrissette mm. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3477-82. doi: 10.1016/s0960-894x(03)00732-7. Bioorg Med Chem Lett. 2003. PMID: 14505652

10

School Closures and Social Anxiety During the COVID-19 Pandemic.

Morrissette M. Morrissette M. J Am Acad Child Adolesc Psychiatry. 2021 Jan;60(1):6-7. doi: 10.1016/j.jaac.2020.08.436. Epub 2020 Sep 2. J Am Acad Child Adolesc Psychiatry. 2021. PMID: 32890669 Free PMC article.

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