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REGγ deficiency promotes premature aging via the casein kinase 1 pathway.
Li L, Zhao D, Wei H, Yao L, Dang Y, Amjad A, Xu J, Liu J, Guo L, Li D, Li Z, Zuo D, Zhang Y, Liu J, Huang S, Jia C, Wang L, Wang Y, Xie Y, Luo J, Zhang B, Luo H, Donehower LA, Moses RE, Xiao J, O'Malley BW, Li X. Li L, et al. Among authors: moses re. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11005-10. doi: 10.1073/pnas.1308497110. Epub 2013 Jun 13. Proc Natl Acad Sci U S A. 2013. PMID: 23766372 Free PMC article.
The proteasome activator REGγ counteracts immunoproteasome expression and autoimmunity.
Yao L, Zhou L, Xuan Y, Zhang P, Wang X, Wang T, Meng T, Xue Y, Ma X, Shah AS, Shang S, Ma X, Xie W, Wang H, Fu Q, Xia Y, Moses RE, Wang H, Li L, Xiao J, Zhang B, Li X. Yao L, et al. Among authors: moses re. J Autoimmun. 2019 Sep;103:102282. doi: 10.1016/j.jaut.2019.05.010. Epub 2019 Jun 4. J Autoimmun. 2019. PMID: 31171475
REGγ ablation impedes dedifferentiation of anaplastic thyroid carcinoma and accentuates radio-therapeutic response by regulating the Smad7-TGF-β pathway.
Jiao C, Li L, Zhang P, Zhang L, Li K, Fang R, Yuan L, Shi K, Pan L, Guo Q, Gao X, Chen G, Xu S, Wang Q, Zuo D, Wu W, Qiao S, Wang X, Moses R, Xiao J, Li L, Dang Y, Li X. Jiao C, et al. Cell Death Differ. 2020 Feb;27(2):497-508. doi: 10.1038/s41418-019-0367-9. Epub 2019 Jun 26. Cell Death Differ. 2020. PMID: 31243343 Free PMC article.
REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway.
Li L, Dang Y, Zhang J, Yan W, Zhai W, Chen H, Li K, Tong L, Gao X, Amjad A, Ji L, Jing T, Jiang Z, Shi K, Yao L, Song D, Liu T, Yang X, Yang C, Cai X, Xu W, Huang Q, He J, Liu J, Chen T, Moses RE, Fu J, Xiao J, Li X. Li L, et al. Among authors: moses re. Nat Commun. 2015 Apr 24;6:6875. doi: 10.1038/ncomms7875. Nat Commun. 2015. PMID: 25908095 Free article.
The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis.
Xu J, Zhou L, Ji L, Chen F, Fortmann K, Zhang K, Liu Q, Li K, Wang W, Wang H, Xie W, Wang Q, Liu J, Zheng B, Zhang P, Huang S, Shi T, Zhang B, Dang Y, Chen J, O'Malley BW, Moses RE, Wang P, Li L, Xiao J, Hoffmann A, Li X. Xu J, et al. Among authors: moses re. Nat Commun. 2016 Feb 22;7:10761. doi: 10.1038/ncomms10761. Nat Commun. 2016. PMID: 26899380 Free PMC article.
144 results