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The obestatin/GPR39 system is up-regulated by muscle injury and functions as an autocrine regenerative system.
Gurriarán-Rodríguez U, Santos-Zas I, Al-Massadi O, Mosteiro CS, Beiroa D, Nogueiras R, Crujeiras AB, Seoane LM, Señarís J, García-Caballero T, Gallego R, Casanueva FF, Pazos Y, Camiña JP. Gurriarán-Rodríguez U, et al. Among authors: mosteiro cs. J Biol Chem. 2012 Nov 2;287(45):38379-89. doi: 10.1074/jbc.M112.374926. Epub 2012 Sep 19. J Biol Chem. 2012. PMID: 22992743 Free PMC article.
Action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling.
Gurriarán-Rodríguez U, Santos-Zas I, González-Sánchez J, Beiroa D, Moresi V, Mosteiro CS, Lin W, Viñuela JE, Señarís J, García-Caballero T, Casanueva FF, Nogueiras R, Gallego R, Renaud JM, Adamo S, Pazos Y, Camiña JP. Gurriarán-Rodríguez U, et al. Among authors: mosteiro cs. Mol Ther. 2015 Jun;23(6):1003-1021. doi: 10.1038/mt.2015.40. Epub 2015 Mar 12. Mol Ther. 2015. PMID: 25762009 Free PMC article.
Preproghrelin expression is a key target for insulin action on adipogenesis.
Gurriarán-Rodríguez U, Al-Massadi O, Crujeiras AB, Mosteiro CS, Amil-Diz M, Beiroa D, Nogueiras R, Seoane LM, Gallego R, Pazos Y, Casanueva FF, Camiña JP. Gurriarán-Rodríguez U, et al. Among authors: mosteiro cs. J Endocrinol. 2011 Aug;210(2):R1-7. doi: 10.1530/JOE-11-0233. Epub 2011 Jun 20. J Endocrinol. 2011. PMID: 21690170
The NMR structure of human obestatin in membrane-like environments: insights into the structure-bioactivity relationship of obestatin.
Alén BO, Nieto L, Gurriarán-Rodríguez U, Mosteiro CS, Álvarez-Pérez JC, Otero-Alén M, Camiña JP, Gallego R, García-Caballero T, Martín-Pastor M, Casanueva FF, Jiménez-Barbero J, Pazos Y. Alén BO, et al. Among authors: mosteiro cs. PLoS One. 2012;7(10):e45434. doi: 10.1371/journal.pone.0045434. Epub 2012 Oct 4. PLoS One. 2012. PMID: 23056203 Free PMC article.
β-Arrestin signal complex plays a critical role in adipose differentiation.
Santos-Zas I, Lodeiro M, Gurriarán-Rodríguez U, Bouzo-Lorenzo M, Mosteiro CS, Casanueva FF, Casabiell X, Pazos Y, Camiña JP. Santos-Zas I, et al. Among authors: mosteiro cs. Int J Biochem Cell Biol. 2013 Jul;45(7):1281-92. doi: 10.1016/j.biocel.2013.03.014. Epub 2013 Apr 1. Int J Biochem Cell Biol. 2013. PMID: 23557604
The role of the obestatin/GPR39 system in human gastric adenocarcinomas.
Alén BO, Leal-López S, Alén MO, Viaño P, García-Castro V, Mosteiro CS, Beiras A, Casanueva FF, Gallego R, García-Caballero T, Camiña JP, Pazos Y. Alén BO, et al. Among authors: mosteiro cs. Oncotarget. 2016 Feb 2;7(5):5957-71. doi: 10.18632/oncotarget.6718. Oncotarget. 2016. PMID: 26716511 Free PMC article.
Obestatin controls the ubiquitin-proteasome and autophagy-lysosome systems in glucocorticoid-induced muscle cell atrophy.
Cid-Díaz T, Santos-Zas I, González-Sánchez J, Gurriarán-Rodríguez U, Mosteiro CS, Casabiell X, García-Caballero T, Mouly V, Pazos Y, Camiña JP. Cid-Díaz T, et al. Among authors: mosteiro cs. J Cachexia Sarcopenia Muscle. 2017 Dec;8(6):974-990. doi: 10.1002/jcsm.12222. Epub 2017 Jul 3. J Cachexia Sarcopenia Muscle. 2017. PMID: 28675664 Free PMC article.
β-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells.
Santos-Zas I, Gurriarán-Rodríguez U, Cid-Díaz T, Figueroa G, González-Sánchez J, Bouzo-Lorenzo M, Mosteiro CS, Señarís J, Casanueva FF, Casabiell X, Gallego R, Pazos Y, Mouly V, Camiña JP. Santos-Zas I, et al. Among authors: mosteiro cs. Cell Mol Life Sci. 2016 Feb;73(3):617-35. doi: 10.1007/s00018-015-1994-z. Epub 2015 Jul 27. Cell Mol Life Sci. 2016. PMID: 26211463
16 results