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Proenkephalin deletion in hematopoietic cells induces intestinal barrier failure resulting in clinical feature similarities with irritable bowel syndrome in mice.
Mas-Orea X, Rey L, Battut L, Bories C, Petitfils C, Abot A, Gheziel N, Wemelle E, Blanpied C, Motta JP, Knauf C, Barreau F, Espinosa E, Aloulou M, Cenac N, Serino M, Mouledous L, Fazilleau N, Dietrich G. Mas-Orea X, et al. Among authors: motta jp. Commun Biol. 2023 Nov 16;6(1):1168. doi: 10.1038/s42003-023-05542-2. Commun Biol. 2023. PMID: 37968381 Free PMC article.
Epithelial expression and function of trypsin-3 in irritable bowel syndrome.
Rolland-Fourcade C, Denadai-Souza A, Cirillo C, Lopez C, Jaramillo JO, Desormeaux C, Cenac N, Motta JP, Larauche M, Taché Y, Vanden Berghe P, Neunlist M, Coron E, Kirzin S, Portier G, Bonnet D, Alric L, Vanner S, Deraison C, Vergnolle N. Rolland-Fourcade C, et al. Among authors: motta jp. Gut. 2017 Oct;66(10):1767-1778. doi: 10.1136/gutjnl-2016-312094. Epub 2017 Jan 17. Gut. 2017. PMID: 28096305 Free PMC article.
Active thrombin produced by the intestinal epithelium controls mucosal biofilms.
Motta JP, Denadai-Souza A, Sagnat D, Guiraud L, Edir A, Bonnart C, Sebbag M, Rousset P, Lapeyre A, Seguy C, Mathurine-Thomas N, Galipeau HJ, Bonnet D, Alric L, Buret AG, Wallace JL, Dufour A, Verdu EF, Hollenberg MD, Oswald E, Serino M, Deraison C, Vergnolle N. Motta JP, et al. Nat Commun. 2019 Jul 19;10(1):3224. doi: 10.1038/s41467-019-11140-w. Nat Commun. 2019. PMID: 31324782 Free PMC article.
Uropathogenic E. coli induces DNA damage in the bladder.
Chagneau CV, Massip C, Bossuet-Greif N, Fremez C, Motta JP, Shima A, Besson C, Le Faouder P, Cénac N, Roth MP, Coppin H, Fontanié M, Martin P, Nougayrède JP, Oswald E. Chagneau CV, et al. Among authors: motta jp. PLoS Pathog. 2021 Feb 25;17(2):e1009310. doi: 10.1371/journal.ppat.1009310. eCollection 2021 Feb. PLoS Pathog. 2021. PMID: 33630958 Free PMC article.
Identification of bacterial lipopeptides as key players in IBS.
Petitfils C, Maurel S, Payros G, Hueber A, Agaiz B, Gazzo G, Marrocco R, Auvray F, Langevin G, Motta JP, Floch P, Tremblay-Franco M, Galano JM, Guy A, Durand T, Lachambre S, Durbec A, Hussein H, Decraecker L, Bertrand-Michel J, Saoudi A, Oswald E, Poisbeau P, Dietrich G, Melchior C, Boeckxstaens G, Serino M, Le Faouder P, Cenac N. Petitfils C, et al. Among authors: motta jp. Gut. 2023 May;72(5):939-950. doi: 10.1136/gutjnl-2022-328084. Epub 2022 Oct 14. Gut. 2023. PMID: 36241390 Free PMC article.
Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.
Motta JP, Magne L, Descamps D, Rolland C, Squarzoni-Dale C, Rousset P, Martin L, Cenac N, Balloy V, Huerre M, Fröhlich LF, Jenne D, Wartelle J, Belaaouaj A, Mas E, Vinel JP, Alric L, Chignard M, Vergnolle N, Sallenave JM. Motta JP, et al. Gastroenterology. 2011 Apr;140(4):1272-82. doi: 10.1053/j.gastro.2010.12.050. Epub 2011 Jan 1. Gastroenterology. 2011. PMID: 21199654
LC-MS/MS method for rapid and concomitant quantification of pro-inflammatory and pro-resolving polyunsaturated fatty acid metabolites.
Le Faouder P, Baillif V, Spreadbury I, Motta JP, Rousset P, Chêne G, Guigné C, Tercé F, Vanner S, Vergnolle N, Bertrand-Michel J, Dubourdeau M, Cenac N. Le Faouder P, et al. Among authors: motta jp. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Aug 1;932:123-33. doi: 10.1016/j.jchromb.2013.06.014. Epub 2013 Jun 15. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 23831705
45 results