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Year Number of Results
2001 1
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2004 4
2005 2
2007 2
2008 3
2009 6
2010 2
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2012 5
2013 8
2014 4
2015 3
2016 3
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Page 1
LKB1 deficiency upregulates RELM-alpha to drive airway goblet cell metaplasia.
Li Y, Zhang Q, Li L, Hao D, Cheng P, Li K, Li X, Wang J, Wang Q, Du Z, Ji H, Chen H. Li Y, et al. Cell Mol Life Sci. 2021 Dec 18;79(1):42. doi: 10.1007/s00018-021-04044-w. Cell Mol Life Sci. 2021. PMID: 34921639 Free PMC article.
An organoid culture study demonstrated that Lkb1 deficiency in mouse airway (club) progenitor cells promoted the expression of FIZZ1/RELM-alpha, which drove airway goblet cell differentiation and pulmonary macrophage recruitment. Additionally, monocyte-derive …
An organoid culture study demonstrated that Lkb1 deficiency in mouse airway (club) progenitor cells promoted the expression of FIZZ1/ …
Here, there and everywhere: Resistin-like molecules in infection, inflammation, and metabolic disorders.
Pine GM, Batugedara HM, Nair MG. Pine GM, et al. Cytokine. 2018 Oct;110:442-451. doi: 10.1016/j.cyto.2018.05.014. Epub 2018 Jun 1. Cytokine. 2018. PMID: 29866514 Free PMC article. Review.
The Resistin-Like Molecules (RELM) alpha, beta, and gamma and their namesake, resistin, share structural and sequence homology but exhibit significant diversity in expression and function within their mammalian host. ...In this review, we will first summarize the mo …
The Resistin-Like Molecules (RELM) alpha, beta, and gamma and their namesake, resistin, share structural and sequence homology …
Allergen-induced resistin-like molecule-alpha promotes esophageal epithelial cell hyperplasia in eosinophilic esophagitis.
Mavi P, Niranjan R, Dutt P, Zaidi A, Shukla JS, Korfhagen T, Mishra A. Mavi P, et al. Am J Physiol Gastrointest Liver Physiol. 2014 Sep 1;307(5):G499-507. doi: 10.1152/ajpgi.00141.2014. Epub 2014 Jul 3. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 24994859 Free PMC article.
Furthermore, to understand the in vivo role of Relm-alpha, we generated Relm-alpha gene-inducible bitransgenic mice by using lung-specific CC-10 promoter (CC10-rtTA-Relm-alpha). We found Relm-alpha protein is signific …
Furthermore, to understand the in vivo role of Relm-alpha, we generated Relm-alpha gene-inducible bitransgenic …
Resistin-like molecule-beta (RELM-beta) targets airways fibroblasts to effect remodelling in asthma: from mouse to man.
Fang CL, Yin LJ, Sharma S, Kierstein S, Wu HF, Eid G, Haczku A, Corrigan CJ, Ying S. Fang CL, et al. Clin Exp Allergy. 2015 May;45(5):940-952. doi: 10.1111/cea.12481. Clin Exp Allergy. 2015. PMID: 25545115 Free PMC article.
METHODS: The effects of RELM-beta gene deficiency were studied in a model of allergen exposure in mice sensitised and challenged with Aspergillus fumigatus (Af). ...Af-induced expression of mRNA encoding some, but not all ECM in the lung parenchyma was attenuated in …
METHODS: The effects of RELM-beta gene deficiency were studied in a model of allergen exposure in mice sensitised and challeng …
Regulation of RELM/FIZZ isoform expression by Cdx2 in response to innate and adaptive immune stimulation in the intestine.
Wang ML, Shin ME, Knight PA, Artis D, Silberg DG, Suh E, Wu GD. Wang ML, et al. Am J Physiol Gastrointest Liver Physiol. 2005 May;288(5):G1074-83. doi: 10.1152/ajpgi.00442.2004. Epub 2004 Dec 2. Am J Physiol Gastrointest Liver Physiol. 2005. PMID: 15576623 Free article.
This was confirmed in vivo using transgenic mice, where ectopic gastric and hepatic expression of Cdx2 induces expression of RELM beta, but not RELM alpha or RELM gamma, exclusively in the stomach. Although there was no quantitative change in co …
This was confirmed in vivo using transgenic mice, where ectopic gastric and hepatic expression of Cdx2 induces expression of RELM …
Alternatively activated macrophage-derived RELM-{alpha} is a negative regulator of type 2 inflammation in the lung.
Nair MG, Du Y, Perrigoue JG, Zaph C, Taylor JJ, Goldschmidt M, Swain GP, Yancopoulos GD, Valenzuela DM, Murphy A, Karow M, Stevens S, Pearce EJ, Artis D. Nair MG, et al. J Exp Med. 2009 Apr 13;206(4):937-52. doi: 10.1084/jem.20082048. Epub 2009 Apr 6. J Exp Med. 2009. PMID: 19349464 Free PMC article.
We describe the generation of RELM-alpha-deficient (Retnla(-/-)) mice and use a model of T helper type 2 (Th2) cytokine-dependent lung inflammation to identify an immunoregulatory role for RELM-alpha. ...Consistent with immunoregulatory properti …
We describe the generation of RELM-alpha-deficient (Retnla(-/-)) mice and use a model of T helper type 2 (Th2) cytokine …
Resistin-like molecule-alpha regulates IL-13-induced chemokine production but not allergen-induced airway responses.
Munitz A, Cole ET, Karo-Atar D, Finkelman FD, Rothenberg ME. Munitz A, et al. Am J Respir Cell Mol Biol. 2012 May;46(5):703-13. doi: 10.1165/rcmb.2011-0391OC. Epub 2012 Jan 12. Am J Respir Cell Mol Biol. 2012. PMID: 22246861 Free PMC article.
Resistin-like molecule alpha (Relm-alpha) is one of the most up-regulated gene products in allergen- and parasite-associated Th2 responses. ...Studies performed with Retnla gene-targeted mice demonstrate that Relm-alpha was largely redund …
Resistin-like molecule alpha (Relm-alpha) is one of the most up-regulated gene products in allergen- and parasite-assoc …
Resistin and RELM-alpha gene expression in white adipose tissue of lactating mice.
Bing C, Gomez-Ambrosi J, Zabalegui N, Williams G, Trayhurn P. Bing C, et al. Biochem Biophys Res Commun. 2002 Aug 16;296(2):458-62. doi: 10.1016/s0006-291x(02)00846-x. Biochem Biophys Res Commun. 2002. PMID: 12163041
This study has examined the expression of the resistin and resistin-like molecule-alpha (RELM-alpha) genes in white adipose tissue of lactating mice. ...These results indicate that the substantial reduction of adiposity in lactation does not lead to an …
This study has examined the expression of the resistin and resistin-like molecule-alpha (RELM-alpha) genes in white adi …
Resistin-like molecule alpha decreases glucose tolerance during intestinal inflammation.
Munitz A, Seidu L, Cole ET, Ahrens R, Hogan SP, Rothenberg ME. Munitz A, et al. J Immunol. 2009 Feb 15;182(4):2357-63. doi: 10.4049/jimmunol.0803130. J Immunol. 2009. PMID: 19201890 Free PMC article.
Resistin-like molecule alpha (Relm-alpha) is a secreted cysteine-rich protein belonging to a newly defined family of proteins, including resistin, Relm-beta, and Relm-gamma. ...Following DSS exposure, serum level of Relm-alpha was …
Resistin-like molecule alpha (Relm-alpha) is a secreted cysteine-rich protein belonging to a newly defined family of pr …
Resistin-like molecule alpha enhances myeloid cell activation and promotes colitis.
Munitz A, Waddell A, Seidu L, Cole ET, Ahrens R, Hogan SP, Rothenberg ME. Munitz A, et al. J Allergy Clin Immunol. 2008 Dec;122(6):1200-1207.e1. doi: 10.1016/j.jaci.2008.10.017. J Allergy Clin Immunol. 2008. PMID: 19084112 Free PMC article.
Yet the function of Relm-alpha remains unknown. OBJECTIVE: We sough to determine the role of Relm-alpha in dextran sodium sulfate (DSS)-induced colonic injury. ...In vivo administration of Relm-alpha initiated cellular recruitment to the …
Yet the function of Relm-alpha remains unknown. OBJECTIVE: We sough to determine the role of Relm-alpha in dextr …
60 results