Mowat CG - Search Results

1

Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase.

Forouhar F, Anderson JL, Mowat CG, Vorobiev SM, Hussain A, Abashidze M, Bruckmann C, Thackray SJ, Seetharaman J, Tucker T, Xiao R, Ma LC, Zhao L, Acton TB, Montelione GT, Chapman SK, Tong L. Forouhar F, et al. Among authors: mowat cg. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):473-8. doi: 10.1073/pnas.0610007104. Epub 2006 Dec 29. Proc Natl Acad Sci U S A. 2007. PMID: 17197414 Free PMC article.

2

Exploring the mechanism of tryptophan 2,3-dioxygenase.

Thackray SJ, Mowat CG, Chapman SK. Thackray SJ, et al. Among authors: mowat cg. Biochem Soc Trans. 2008 Dec;36(Pt 6):1120-3. doi: 10.1042/BST0361120. Biochem Soc Trans. 2008. PMID: 19021508 Free PMC article. Review.

3

Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding.

Thackray SJ, Bruckmann C, Anderson JL, Campbell LP, Xiao R, Zhao L, Mowat CG, Forouhar F, Tong L, Chapman SK. Thackray SJ, et al. Among authors: mowat cg. Biochemistry. 2008 Oct 7;47(40):10677-84. doi: 10.1021/bi801202a. Epub 2008 Sep 11. Biochemistry. 2008. PMID: 18783250

4

Probing the ternary complexes of indoleamine and tryptophan 2,3-dioxygenases by cryoreduction EPR and ENDOR spectroscopy.

Davydov RM, Chauhan N, Thackray SJ, Anderson JL, Papadopoulou ND, Mowat CG, Chapman SK, Raven EL, Hoffman BM. Davydov RM, et al. Among authors: mowat cg. J Am Chem Soc. 2010 Apr 21;132(15):5494-500. doi: 10.1021/ja100518z. J Am Chem Soc. 2010. PMID: 20353179 Free PMC article.

5

The mechanism of substrate inhibition in human indoleamine 2,3-dioxygenase.

Efimov I, Basran J, Sun X, Chauhan N, Chapman SK, Mowat CG, Raven EL. Efimov I, et al. Among authors: mowat cg. J Am Chem Soc. 2012 Feb 15;134(6):3034-41. doi: 10.1021/ja208694g. Epub 2012 Feb 2. J Am Chem Soc. 2012. PMID: 22299628 Free PMC article.

6

Binding of l-kynurenine to X. campestris tryptophan 2,3-dioxygenase.

Basran J, Booth ES, Campbell LP, Thackray SJ, Jesani MH, Clayden J, Moody PCE, Mowat CG, Kwon H, Raven EL. Basran J, et al. Among authors: mowat cg. J Inorg Biochem. 2021 Dec;225:111604. doi: 10.1016/j.jinorgbio.2021.111604. Epub 2021 Sep 16. J Inorg Biochem. 2021. PMID: 34571402

7

Reassessment of the reaction mechanism in the heme dioxygenases.

Chauhan N, Thackray SJ, Rafice SA, Eaton G, Lee M, Efimov I, Basran J, Jenkins PR, Mowat CG, Chapman SK, Raven EL. Chauhan N, et al. Among authors: mowat cg. J Am Chem Soc. 2009 Apr 1;131(12):4186-7. doi: 10.1021/ja808326g. J Am Chem Soc. 2009. PMID: 19275153

8

Altered substrate specificity in flavocytochrome b2: structural insights into the mechanism of L-lactate dehydrogenation.

Mowat CG, Wehenkel A, Green AJ, Walkinshaw MD, Reid GA, Chapman SK. Mowat CG, et al. Biochemistry. 2004 Jul 27;43(29):9519-26. doi: 10.1021/bi049263m. Biochemistry. 2004. PMID: 15260495

9

Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation.

Mowat CG, Rothery E, Miles CS, McIver L, Doherty MK, Drewette K, Taylor P, Walkinshaw MD, Chapman SK, Reid GA. Mowat CG, et al. Nat Struct Mol Biol. 2004 Oct;11(10):1023-4. doi: 10.1038/nsmb827. Epub 2004 Sep 7. Nat Struct Mol Biol. 2004. PMID: 15361860

10

Multi-heme cytochromes--new structures, new chemistry.

Mowat CG, Chapman SK. Mowat CG, et al. Dalton Trans. 2005 Nov 7;(21):3381-9. doi: 10.1039/b505184c. Epub 2005 Sep 26. Dalton Trans. 2005. PMID: 16234915

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