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WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones.
Moya B, Barcelo IM, Bhagwat S, Patel M, Bou G, Papp-Wallace KM, Bonomo RA, Oliver A. Moya B, et al. Antimicrob Agents Chemother. 2017 May 24;61(6):e02529-16. doi: 10.1128/AAC.02529-16. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28289035 Free PMC article.
Four Decades of β-Lactam Antibiotic Pharmacokinetics in Cystic Fibrosis.
Bulitta JB, Jiao Y, Drescher SK, Oliver A, Louie A, Moya B, Tao X, Wittau M, Tsuji BT, Zavascki AP, Shin BS, Drusano GL, Sörgel F, Landersdorfer CB. Bulitta JB, et al. Among authors: moya b. Clin Pharmacokinet. 2019 Feb;58(2):143-156. doi: 10.1007/s40262-018-0678-x. Clin Pharmacokinet. 2019. PMID: 29936678 Review.
First population pharmacokinetic analysis showing increased quinolone metabolite formation and clearance in patients with cystic fibrosis compared to healthy volunteers.
Jiao Y, Kim TH, Tao X, Kinzig M, Landersdorfer CB, Drescher SK, Sutaria DS, Moya B, Holzgrabe U, Sörgel F, Bulitta JB. Jiao Y, et al. Among authors: moya b. Eur J Pharm Sci. 2018 Oct 15;123:416-428. doi: 10.1016/j.ejps.2018.07.054. Epub 2018 Aug 1. Eur J Pharm Sci. 2018. PMID: 30076955
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