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MRPL13 is a Prognostic Cancer Biomarker and Correlates with Immune Infiltrates in Breast Cancer.
Tao Z, Suo H, Zhang L, Jin Z, Wang Z, Wang D, Wu M, Peng N, Zhao Y, Chen B. Tao Z, et al. Onco Targets Ther. 2020 Nov 27;13:12255-12268. doi: 10.2147/OTT.S263998. eCollection 2020. Onco Targets Ther. 2020. PMID: 33273831 Free PMC article.
The GSEA method was used to predict the possible regulatory pathways of MRPL13. Immune responses of MRPL13 expression were analyzed using TISIDB and CIBERSORT. ...Furthermore, PCR showed that MRPL13 affected VEGFA and MMP gene expression. CIBERSORT analysis r …
The GSEA method was used to predict the possible regulatory pathways of MRPL13. Immune responses of MRPL13 expression were ana …
MRPL13 Promotes Tumor Cell Proliferation, Migration and EMT Process in Breast Cancer Through the PI3K-AKT-mTOR Pathway.
Cai M, Li H, Chen R, Zhou X. Cai M, et al. Cancer Manag Res. 2021 Feb 25;13:2009-2024. doi: 10.2147/CMAR.S296038. eCollection 2021. Cancer Manag Res. 2021. PMID: 33658859 Free PMC article.
The purpose of the current study was to evaluate the prognostic significance of MRPL13, as well as to explore its potential biological functions in BC. ...Knockdown of MRPL13 restrains the proliferation and migration potential and EMT process of BC through inhibitin …
The purpose of the current study was to evaluate the prognostic significance of MRPL13, as well as to explore its potential biologica …
MRPL13 Act as a Novel Therapeutic Target and Could Promote Cell Proliferation in Non-Small Cell Lung Cancer.
Jing C, Fu R, Wang C, Li X, Zhang W. Jing C, et al. Cancer Manag Res. 2021 Jul 12;13:5535-5545. doi: 10.2147/CMAR.S316428. eCollection 2021. Cancer Manag Res. 2021. PMID: 34285575 Free PMC article.
BACKGROUND: The latent involvement of MRPL13 in non-small cell lung cancer (NSCLC) remains unclear. This study aimed to explore the role of MRPL13 in NSCLC. ...In vitro experiments showed that MRPL13 was highly expressed in NSCLC tissue and cell lines. MRP …
BACKGROUND: The latent involvement of MRPL13 in non-small cell lung cancer (NSCLC) remains unclear. This study aimed to explore the r …
Elp3-mediated codon-dependent translation promotes mTORC2 activation and regulates macrophage polarization.
Chen D, Nemazanyy I, Peulen O, Shostak K, Xu X, Tang SC, Wathieu C, Turchetto S, Tielens S, Nguyen L, Close P, Desmet C, Klein S, Florin A, Büttner R, Petrellis G, Dewals B, Chariot A. Chen D, et al. EMBO J. 2022 Sep 15;41(18):e109353. doi: 10.15252/embj.2021109353. Epub 2022 Aug 3. EMBO J. 2022. PMID: 35920020 Free PMC article.
The metabolic reprogramming linked to M2 macrophage polarization relies on Elp3 and the translation of multiple candidates, including the mitochondrial ribosome large subunit proteins Mrpl3, Mrpl13, and Mrpl47. By promoting translation of its activator Ric8b in a codon-dep …
The metabolic reprogramming linked to M2 macrophage polarization relies on Elp3 and the translation of multiple candidates, including the mi …
Multi-omics analysis of MRPL-13 as a tumor-promoting marker from pan-cancer to lung adenocarcinoma.
Zhong X, He Z, Fan Y, Yin L, Hong Z, Tong Y, Bi Q, Zhu S. Zhong X, et al. Aging (Albany NY). 2023 Oct 12;15(19):10640-10680. doi: 10.18632/aging.205104. Epub 2023 Oct 12. Aging (Albany NY). 2023. PMID: 37827692 Free PMC article.
However, a thorough examination of MRPL13 across cancers remains uncertain. Therefore, we tried to clarify the relationship between MRPL13 and pan-cancer, and verified it in lung adenocarcinoma by various methods. ...Finally, the effect of knocking out MRPL13 …
However, a thorough examination of MRPL13 across cancers remains uncertain. Therefore, we tried to clarify the relationship between …
Identification of the Upregulation of MRPL13 as a Novel Prognostic Marker Associated with Overall Survival Time and Immunotherapy Response in Breast Cancer.
Ye H, Zhang N. Ye H, et al. Comput Math Methods Med. 2021 Nov 25;2021:1498924. doi: 10.1155/2021/1498924. eCollection 2021. Comput Math Methods Med. 2021. PMID: 34868337 Free PMC article.
Moreover, we revealed higher expression of MRPL13 was significantly correlated to shorter OS time and higher TMB levels in BRCA. Pan-cancer analysis further revealed the prognostic value of MRPL13 in human cancers. MRPL13 expression was significantly increase …
Moreover, we revealed higher expression of MRPL13 was significantly correlated to shorter OS time and higher TMB levels in BRCA. Pan- …
[High expression of MRPL13 promotes cell cycle progression and proliferation of gastric cancer cells by inhibiting p53 signaling to affect long-term prognosis].
Wang L, Xia Y, Zhang Z, Liu X, Shi J, Wang Y, Li J, Zhnag X, Geng Z, Song X, Zuo L. Wang L, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2023 Sep 20;43(9):1558-1566. doi: 10.12122/j.issn.1673-4254.2023.09.13. Nan Fang Yi Ke Da Xue Xue Bao. 2023. PMID: 37814870 Free PMC article. Chinese.
MRPL13 overexpression significantly promoted gastric cancer cell xenograft growth (P<0.05), and MRPL13 knockdown obviously inhibited tumor growth in nude mice (P<0.05). In both cultured gastric cancer cells and the xenografts in nude mice, MRPL13 overex …
MRPL13 overexpression significantly promoted gastric cancer cell xenograft growth (P<0.05), and MRPL13 knockdown obviously …
In silico analyses of pan-squamous cell carcinoma unveiled the immunological implications of MRPL13, which had previously been under-recognized.
Liang Y, He S, Tan Y, Liu Q, Zhao F, Liu T, Huang C, Lu X, Zheng S. Liang Y, et al. Heliyon. 2023 Dec 14;10(1):e23582. doi: 10.1016/j.heliyon.2023.e23582. eCollection 2024 Jan 15. Heliyon. 2023. PMID: 38187248 Free PMC article.
However, the clinicopathological significance of MRPL13 in squamous cell carcinoma (SCC) remains poorly understood. ...Through these pan-SCC analyses, we have expanded the understanding of MRPL13 previously reported, in particular, underscoring the immunological inv …
However, the clinicopathological significance of MRPL13 in squamous cell carcinoma (SCC) remains poorly understood. ...Through these …
39 results