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2002 1
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MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Zhang W, Yu L, Xu C, Tang T, Cao J, Chen L, Pang X, Ren W. Zhang W, et al. Oncol Lett. 2023 May 26;26(1):298. doi: 10.3892/ol.2023.13884. eCollection 2023 Jul. Oncol Lett. 2023. PMID: 37323822 Free PMC article.
Patients with LUAD and higher MRPL51 expression had a significantly shorter overall survival (OS). ...High MRPL51 expression may be a prognostic biomarker indicating poor OS....
Patients with LUAD and higher MRPL51 expression had a significantly shorter overall survival (OS). ...High MRPL51 expression m …
Development and Validation of a DNA Methylation-related Classifier of Circulating Tumour Cells to Predict Prognosis and to provide a therapeutic strategy in Lung Adenocarcinoma.
Gu X, Huang X, Zhang X, Wang C. Gu X, et al. Int J Biol Sci. 2022 Aug 1;18(13):4984-5000. doi: 10.7150/ijbs.75284. eCollection 2022. Int J Biol Sci. 2022. PMID: 35982906 Free PMC article.
Results: Three differentially methylated genes (DMGs) of CTCs for LUAD, including mitochondrial ribosomal protein L51 (MRPL51), STE20-like kinase (SLK), and protein regulator of cytokinesis 1(PRC1), were effectively used to construct a risk model. ...
Results: Three differentially methylated genes (DMGs) of CTCs for LUAD, including mitochondrial ribosomal protein L51 (MRPL51), STE20 …
Reverse genetic analysis of yeast YPR099C/MRPL51 reveals a critical role of both overlapping ORFs in respiratory growth and MRPL51 in mitochondrial DNA maintenance.
Sahu PK, Salim S, Pp M, Chauhan S, Tomar RS. Sahu PK, et al. FEMS Yeast Res. 2019 Sep 1;19(6):foz056. doi: 10.1093/femsyr/foz056. FEMS Yeast Res. 2019. PMID: 31374566
Our study characterizes a dubious/nondubious ORF pair, YPR099C/MRPL51, and shows the transcript and protein level expression of YPR099C. ...Both the ORFs were found essential for the functional mitochondria and respiratory growth, but MRPL51 showed its specific requ …
Our study characterizes a dubious/nondubious ORF pair, YPR099C/MRPL51, and shows the transcript and protein level expression of YPR09 …
Integrative analysis of circadian clock with prognostic and immunological biomarker identification in ovarian cancer.
Zhao L, Tang Y, Yang J, Lin F, Liu X, Zhang Y, Chen J. Zhao L, et al. Front Mol Biosci. 2023 Jun 20;10:1208132. doi: 10.3389/fmolb.2023.1208132. eCollection 2023. Front Mol Biosci. 2023. PMID: 37409345 Free PMC article.
WGCNA screened the green gene module to be mostly correlated with CCI and CCI group, which was utilized to construct a PPI network to pick out 15 hub genes (RNF169, EDC4, CHCHD1, MRPL51, UQCC2, USP34, POM121, RPL37, SNRPC, LAMTOR5, MRPL52, LAMTOR4, NDUFB1, NDUFC1, POLR3K) …
WGCNA screened the green gene module to be mostly correlated with CCI and CCI group, which was utilized to construct a PPI network to pick o …
Systematic Analysis and Biomarker Study for Alzheimer's Disease.
Li X, Wang H, Long J, Pan G, He T, Anichtchik O, Belshaw R, Albani D, Edison P, Green EK, Scott J. Li X, et al. Sci Rep. 2018 Nov 26;8(1):17394. doi: 10.1038/s41598-018-35789-3. Sci Rep. 2018. PMID: 30478411 Free PMC article.
We identified 789 and 998 DEGs common to both blood and brain of AD and MCI subjects respectively, over 77% of which had the same regulation directions across tissues and disease status, including the known ABCA7, and the novel TYK2 and TCIRG1. A machine learning classification m …
We identified 789 and 998 DEGs common to both blood and brain of AD and MCI subjects respectively, over 77% of which had the same regulation …
CRISPR/Cas9-mediated whole genomic wide knockout screening identifies mitochondrial ribosomal proteins involving in oxygen-glucose deprivation/reperfusion resistance.
Guan X, Zhang H, Qin H, Chen C, Hu Z, Tan J, Zeng L. Guan X, et al. J Cell Mol Med. 2020 Aug;24(16):9313-9322. doi: 10.1111/jcmm.15580. Epub 2020 Jul 2. J Cell Mol Med. 2020. PMID: 32618081 Free PMC article.
We then knocked down some of the identified candidate genes individually. We demonstrated that MRPL19, MRPL32, MRPL52 and MRPL51 inhibition increased cell viability and attenuated OGDR-induced apoptosis. ...MRPL19 and MRPL51 contribute to OGDR resistance and are sup …
We then knocked down some of the identified candidate genes individually. We demonstrated that MRPL19, MRPL32, MRPL52 and MRPL51 inhi …
Altered expression of Armet and Mrlp51 in the oocyte, preimplantation embryo, and brain of mice following oocyte in vitro maturation but postnatal brain development and cognitive function are normal.
Wang N, Wang L, Le F, Zhan Q, Zheng Y, Ding G, Chen X, Sheng J, Dong M, Huang H, Jin F. Wang N, et al. Reproduction. 2011 Sep;142(3):401-8. doi: 10.1530/REP-11-0152. Epub 2011 Jul 5. Reproduction. 2011. PMID: 21730110
Thirteen genes were upregulated in IVM oocytes compared with the control, including Armet and Mrpl51. The higher level of Armet in IVM oocytes was retained in brain of newborn mice, which could be related to the upregulation of activating transcription factor 6 (Atf6) and …
Thirteen genes were upregulated in IVM oocytes compared with the control, including Armet and Mrpl51. The higher level of Armet in IV …
Aberrant mitochondrial homeostasis at the crossroad of musculoskeletal ageing and non-small cell lung cancer.
Prokopidis K, Giannos P, Witard OC, Peckham D, Ispoglou T. Prokopidis K, et al. PLoS One. 2022 Sep 6;17(9):e0273766. doi: 10.1371/journal.pone.0273766. eCollection 2022. PLoS One. 2022. PMID: 36067173 Free PMC article.
The analysis revealed that the dysregulated expression of the mammalian mitochondrial ribosomal proteins, Mitochondrial Ribosomal Protein S26 (MRPS26), Mitochondrial Ribosomal Protein S17 (MRPS17), Mitochondrial Ribosomal Protein L18 (MRPL18) and Mitochondrial Ribosomal Protein L …
The analysis revealed that the dysregulated expression of the mammalian mitochondrial ribosomal proteins, Mitochondrial Ribosomal Protein S2 …
Properties of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L and its interactions with mammalian mitochondrial ribosomes.
Haque ME, Elmore KB, Tripathy A, Koc H, Koc EC, Spremulli LL. Haque ME, et al. J Biol Chem. 2010 Sep 3;285(36):28353-62. doi: 10.1074/jbc.M110.148262. Epub 2010 Jul 2. J Biol Chem. 2010. PMID: 20601428 Free PMC article.
Oxa1L-CTT cross-links to mammalian mitochondrial homologs of the bacterial ribosomal proteins L13, L20, and L28 and to mammalian mitochondrial specific ribosomal proteins MRPL48, MRPL49, and MRPL51. Oxa1L-CTT does not cross-link to proteins decorating the conventional exit …
Oxa1L-CTT cross-links to mammalian mitochondrial homologs of the bacterial ribosomal proteins L13, L20, and L28 and to mammalian mitochondri …
13 results