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Cytochrome c is released in a single step during apoptosis.
Goldstein JC, Muñoz-Pinedo C, Ricci JE, Adams SR, Kelekar A, Schuler M, Tsien RY, Green DR. Goldstein JC, et al. Cell Death Differ. 2005 May;12(5):453-62. doi: 10.1038/sj.cdd.4401596. Cell Death Differ. 2005. PMID: 15933725
Measuring apoptosis at the single cell level.
Bouchier-Hayes L, Muñoz-Pinedo C, Connell S, Green DR. Bouchier-Hayes L, et al. Methods. 2008 Mar;44(3):222-8. doi: 10.1016/j.ymeth.2007.11.007. Methods. 2008. PMID: 18314052 Free PMC article. Review.
Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells.
Godoy LC, Muñoz-Pinedo C, Castro L, Cardaci S, Schonhoff CM, King M, Tórtora V, Marín M, Miao Q, Jiang JF, Kapralov A, Jemmerson R, Silkstone GG, Patel JN, Evans JE, Wilson MT, Green DR, Kagan VE, Radi R, Mannick JB. Godoy LC, et al. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2653-8. doi: 10.1073/pnas.0809279106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196960 Free PMC article.
63 results