Muga A - Search Results

1

Quantitative super-resolution imaging of pathological aggregates reveals distinct toxicity profiles in different synucleinopathies.

Morten MJ, Sirvio L, Rupawala H, Mee Hayes E, Franco A, Radulescu C, Ying L, Barnes SJ, Muga A, Ye Y. Morten MJ, et al. Among authors: muga a. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2205591119. doi: 10.1073/pnas.2205591119. Epub 2022 Oct 7. Proc Natl Acad Sci U S A. 2022. PMID: 36206368 Free PMC article.

2

All-or-none amyloid disassembly via chaperone-triggered fibril unzipping favors clearance of α-synuclein toxic species.

Franco A, Gracia P, Colom A, Camino JD, Fernández-Higuero JÁ, Orozco N, Dulebo A, Saiz L, Cremades N, Vilar JMG, Prado A, Muga A. Franco A, et al. Among authors: muga a. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2105548118. doi: 10.1073/pnas.2105548118. Proc Natl Acad Sci U S A. 2021. PMID: 34462355 Free PMC article.

3

Unzipping the Secrets of Amyloid Disassembly by the Human Disaggregase.

Franco A, Velasco-Carneros L, Alvarez N, Orozco N, Moro F, Prado A, Muga A. Franco A, et al. Among authors: muga a. Cells. 2021 Oct 14;10(10):2745. doi: 10.3390/cells10102745. Cells. 2021. PMID: 34685723 Free PMC article. Review.

4

Truncation-Driven Lateral Association of α-Synuclein Hinders Amyloid Clearance by the Hsp70-Based Disaggregase.

Franco A, Cuéllar J, Fernández-Higuero JÁ, de la Arada I, Orozco N, Valpuesta JM, Prado A, Muga A. Franco A, et al. Among authors: muga a. Int J Mol Sci. 2021 Nov 30;22(23):12983. doi: 10.3390/ijms222312983. Int J Mol Sci. 2021. PMID: 34884786 Free PMC article.

5

A Quantitative Characterization of Nucleoplasmin/Histone Complexes Reveals Chaperone Versatility.

Fernández-Rivero N, Franco A, Velázquez-Campoy A, Alonso E, Muga A, Prado A. Fernández-Rivero N, et al. Among authors: muga a. Sci Rep. 2016 Aug 25;6:32114. doi: 10.1038/srep32114. Sci Rep. 2016. PMID: 27558753 Free PMC article.

6

Structural insights into the ability of nucleoplasmin to assemble and chaperone histone octamers for DNA deposition.

Franco A, Arranz R, Fernández-Rivero N, Velázquez-Campoy A, Martín-Benito J, Segura J, Prado A, Valpuesta JM, Muga A. Franco A, et al. Among authors: muga a. Sci Rep. 2019 Jul 1;9(1):9487. doi: 10.1038/s41598-019-45726-7. Sci Rep. 2019. PMID: 31263230 Free PMC article.

7

Crowding activates ClpB and enhances its association with DnaK for efficient protein aggregate reactivation.

Martín I, Celaya G, Alfonso C, Moro F, Rivas G, Muga A. Martín I, et al. Among authors: muga a. Biophys J. 2014 May 6;106(9):2017-27. doi: 10.1016/j.bpj.2014.03.042. Biophys J. 2014. PMID: 24806934 Free PMC article.

8

The Complex Phosphorylation Patterns that Regulate the Activity of Hsp70 and Its Cochaperones.

Velasco L, Dublang L, Moro F, Muga A. Velasco L, et al. Among authors: muga a. Int J Mol Sci. 2019 Aug 23;20(17):4122. doi: 10.3390/ijms20174122. Int J Mol Sci. 2019. PMID: 31450862 Free PMC article. Review.

9

Extraction and Refolding Determinants of Chaperone-Driven Aggregated Protein Reactivation.

Fernández-Higuero JA, Muga A, Vilar JMG. Fernández-Higuero JA, et al. Among authors: muga a. J Mol Biol. 2020 May 1;432(10):3239-3250. doi: 10.1016/j.jmb.2020.03.002. Epub 2020 Mar 5. J Mol Biol. 2020. PMID: 32147456

10

Chaperone-assisted protein aggregate reactivation: Different solutions for the same problem.

Aguado A, Fernández-Higuero JA, Moro F, Muga A. Aguado A, et al. Among authors: muga a. Arch Biochem Biophys. 2015 Aug 15;580:121-34. doi: 10.1016/j.abb.2015.07.006. Epub 2015 Jul 6. Arch Biochem Biophys. 2015. PMID: 26159839 Review.

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