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Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F.
Ivanchenko MV, Hathaway DM, Klein AJ, Pan B, Strelkova O, De-la-Torre P, Wu X, Peters CW, Mulhall EM, Booth KT, Goldstein C, Brower J, Sotomayor M, Indzhykulian AA, Corey DP. Ivanchenko MV, et al. Among authors: mulhall em. Nat Commun. 2023 Apr 26;14(1):2400. doi: 10.1038/s41467-023-38038-y. Nat Commun. 2023. PMID: 37100771 Free PMC article.
Direct observation of the conformational states of PIEZO1.
Mulhall EM, Gharpure A, Lee RM, Dubin AE, Aaron JS, Marshall KL, Spencer KR, Reiche MA, Henderson SC, Chew TL, Patapoutian A. Mulhall EM, et al. Nature. 2023 Aug;620(7976):1117-1125. doi: 10.1038/s41586-023-06427-4. Epub 2023 Aug 16. Nature. 2023. PMID: 37587339 Free PMC article.
PCDH15 Dual-AAV Gene Therapy for Deafness and Blindness in Usher Syndrome Type 1F.
Ivanchenko MV, Hathaway DM, Mulhall EM, Booth KT, Wang M, Peters CW, Klein AJ, Chen X, Li Y, György B, Corey DP. Ivanchenko MV, et al. Among authors: mulhall em. bioRxiv [Preprint]. 2023 Nov 13:2023.11.09.566447. doi: 10.1101/2023.11.09.566447. bioRxiv. 2023. PMID: 38014037 Free PMC article. Preprint.