Mulloy JC - Search Results

1

Rapid desensitization of humanized mice with anti-human FcεRIα monoclonal antibodies.

Khodoun MV, Morris SC, Angerman E, Potter C, Schuman R, Wunderlich M, Maciag JJ, Sullivan Locker KC, Mulloy JC, Herr AB, Finkelman FD. Khodoun MV, et al. Among authors: mulloy jc. J Allergy Clin Immunol. 2020 Mar;145(3):907-921.e3. doi: 10.1016/j.jaci.2019.12.003. Epub 2019 Dec 11. J Allergy Clin Immunol. 2020. PMID: 31836406 Free PMC article.

2

AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion.

Mulloy JC, Jankovic V, Wunderlich M, Delwel R, Cammenga J, Krejci O, Zhao H, Valk PJ, Lowenberg B, Nimer SD. Mulloy JC, et al. Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4016-21. doi: 10.1073/pnas.0404701102. Epub 2005 Feb 24. Proc Natl Acad Sci U S A. 2005. PMID: 15731354 Free PMC article.

3

Human CD34+ cells expressing the inv(16) fusion protein exhibit a myelomonocytic phenotype with greatly enhanced proliferative ability.

Wunderlich M, Krejci O, Wei J, Mulloy JC. Wunderlich M, et al. Among authors: mulloy jc. Blood. 2006 Sep 1;108(5):1690-7. doi: 10.1182/blood-2005-12-012773. Epub 2006 May 2. Blood. 2006. PMID: 16670269 Free PMC article.

4

p53 signaling in response to increased DNA damage sensitizes AML1-ETO cells to stress-induced death.

Krejci O, Wunderlich M, Geiger H, Chou FS, Schleimer D, Jansen M, Andreassen PR, Mulloy JC. Krejci O, et al. Among authors: mulloy jc. Blood. 2008 Feb 15;111(4):2190-9. doi: 10.1182/blood-2007-06-093682. Epub 2007 Nov 1. Blood. 2008. PMID: 17975013 Free PMC article.

5

Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.

Wei J, Wunderlich M, Fox C, Alvarez S, Cigudosa JC, Wilhelm JS, Zheng Y, Cancelas JA, Gu Y, Jansen M, Dimartino JF, Mulloy JC. Wei J, et al. Among authors: mulloy jc. Cancer Cell. 2008 Jun;13(6):483-95. doi: 10.1016/j.ccr.2008.04.020. Cancer Cell. 2008. PMID: 18538732 Free PMC article.

6

Transforming human blood stem and progenitor cells: a new way forward in leukemia modeling.

Mulloy JC, Wunderlich M, Zheng Y, Wei J. Mulloy JC, et al. Cell Cycle. 2008 Nov 1;7(21):3314-9. doi: 10.4161/cc.7.21.6951. Epub 2008 Nov 8. Cell Cycle. 2008. PMID: 18948748 Free PMC article.

7

Model systems for examining effects of leukemia-associated oncogenes in primary human CD34+ cells via retroviral transduction.

Wunderlich M, Mulloy JC. Wunderlich M, et al. Among authors: mulloy jc. Methods Mol Biol. 2009;538:263-85. doi: 10.1007/978-1-59745-418-6_13. Methods Mol Biol. 2009. PMID: 19277588 Free PMC article.

8

N-Ras(G12D) induces features of stepwise transformation in preleukemic human umbilical cord blood cultures expressing the AML1-ETO fusion gene.

Chou FS, Wunderlich M, Griesinger A, Mulloy JC. Chou FS, et al. Among authors: mulloy jc. Blood. 2011 Feb 17;117(7):2237-40. doi: 10.1182/blood-2010-01-264119. Epub 2011 Jan 3. Blood. 2011. PMID: 21200020 Free PMC article.

9

Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.

Mizukawa B, Wei J, Shrestha M, Wunderlich M, Chou FS, Griesinger A, Harris CE, Kumar AR, Zheng Y, Williams DA, Mulloy JC. Mizukawa B, et al. Among authors: mulloy jc. Blood. 2011 Nov 10;118(19):5235-45. doi: 10.1182/blood-2011-04-351817. Epub 2011 Sep 22. Blood. 2011. PMID: 21940819 Free PMC article.

10

The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO.

Chou FS, Griesinger A, Wunderlich M, Lin S, Link KA, Shrestha M, Goyama S, Mizukawa B, Shen S, Marcucci G, Mulloy JC. Chou FS, et al. Among authors: mulloy jc. Blood. 2012 Jul 26;120(4):709-19. doi: 10.1182/blood-2012-01-403212. Epub 2012 Feb 14. Blood. 2012. PMID: 22337712 Free PMC article.

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