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Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer.
Heijmans J, Wielenga MC, Rosekrans SL, van Lidth de Jeude JF, Roelofs J, Groothuis P, Ederveen A, de Jonge-Muller ES, Biemond I, Hardwick JC, D'Haens G, Hommes DW, Muncan V, van den Brink GR. Heijmans J, et al. Among authors: muncan v. Gut. 2014 Feb;63(2):310-6. doi: 10.1136/gutjnl-2012-304216. Epub 2013 Feb 13. Gut. 2014. PMID: 23408349
Intestinal tumorigenesis is not affected by progesterone signaling in rodent models.
Heijmans J, Muncan V, Jacobs RJ, de Jonge-Muller ES, Graven L, Biemond I, Ederveen AG, Groothuis PG, Mosselman S, Hardwick JC, Hommes DW, van den Brink GR. Heijmans J, et al. Among authors: muncan v. PLoS One. 2011;6(7):e22620. doi: 10.1371/journal.pone.0022620. Epub 2011 Jul 27. PLoS One. 2011. PMID: 21818351 Free PMC article.
Blimp1 regulates the transition of neonatal to adult intestinal epithelium.
Muncan V, Heijmans J, Krasinski SD, Büller NV, Wildenberg ME, Meisner S, Radonjic M, Stapleton KA, Lamers WH, Biemond I, van den Bergh Weerman MA, O'Carroll D, Hardwick JC, Hommes DW, van den Brink GR. Muncan V, et al. Nat Commun. 2011 Aug 30;2:452. doi: 10.1038/ncomms1463. Nat Commun. 2011. PMID: 21878906 Free PMC article.
Rage signalling promotes intestinal tumourigenesis.
Heijmans J, Büller NV, Hoff E, Dihal AA, van der Poll T, van Zoelen MA, Bierhaus A, Biemond I, Hardwick JC, Hommes DW, Muncan V, van den Brink GR. Heijmans J, et al. Among authors: muncan v. Oncogene. 2013 Feb 28;32(9):1202-6. doi: 10.1038/onc.2012.119. Epub 2012 Apr 2. Oncogene. 2013. PMID: 22469986
Rage mediated DAMP signaling in intestinal tumorigenesis.
Heijmans J, Büller NV, Muncan V, van den Brink GR. Heijmans J, et al. Among authors: muncan v. Oncoimmunology. 2012 Oct 1;1(7):1165-1166. doi: 10.4161/onci.20929. Oncoimmunology. 2012. PMID: 23170266 Free PMC article.
ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response.
Heijmans J, van Lidth de Jeude JF, Koo BK, Rosekrans SL, Wielenga MC, van de Wetering M, Ferrante M, Lee AS, Onderwater JJ, Paton JC, Paton AW, Mommaas AM, Kodach LL, Hardwick JC, Hommes DW, Clevers H, Muncan V, van den Brink GR. Heijmans J, et al. Among authors: muncan v. Cell Rep. 2013 Apr 25;3(4):1128-39. doi: 10.1016/j.celrep.2013.02.031. Epub 2013 Mar 28. Cell Rep. 2013. PMID: 23545496 Free article.
59 results