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Lack of collagen XV impairs peripheral nerve maturation and, when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction.
Rasi K, Hurskainen M, Kallio M, Stavén S, Sormunen R, Heape AM, Avila RL, Kirschner D, Muona A, Tolonen U, Tanila H, Huhtala P, Soininen R, Pihlajaniemi T. Rasi K, et al. Among authors: muona a. J Neurosci. 2010 Oct 27;30(43):14490-501. doi: 10.1523/JNEUROSCI.2644-10.2010. J Neurosci. 2010. PMID: 20980607 Free PMC article.
Lack of type XV collagen causes a skeletal myopathy and cardiovascular defects in mice.
Eklund L, Piuhola J, Komulainen J, Sormunen R, Ongvarrasopone C, Fássler R, Muona A, Ilves M, Ruskoaho H, Takala TE, Pihlajaniemi T. Eklund L, et al. Among authors: muona a. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1194-9. doi: 10.1073/pnas.98.3.1194. Epub 2001 Jan 23. Proc Natl Acad Sci U S A. 2001. PMID: 11158616 Free PMC article.
An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo.
Keuters MH, Keksa-Goldsteine V, Dhungana H, Huuskonen MT, Pomeshchik Y, Savchenko E, Korhonen PK, Singh Y, Wojciechowski S, Lehtonen Š, Kanninen KM, Malm T, Sirviö J, Muona A, Koistinaho M, Goldsteins G, Koistinaho J. Keuters MH, et al. Among authors: muona a. Sci Rep. 2021 Feb 10;11(1):3518. doi: 10.1038/s41598-021-81741-3. Sci Rep. 2021. PMID: 33568697 Free PMC article.