Murphy M - Search Results

1

IHG-1 must be localised to mitochondria to decrease Smad7 expression and amplify TGF-β1-induced fibrotic responses.

Corcoran JB, McCarthy S, Griffin B, Gaffney A, Bhreathnach U, Börgeson E, Hickey FB, Docherty NG, Higgins DF, Furlong F, Martin F, Godson C, Murphy M. Corcoran JB, et al. Among authors: murphy m. Biochim Biophys Acta. 2013 Aug;1833(8):1969-78. doi: 10.1016/j.bbamcr.2013.03.027. Epub 2013 Apr 6. Biochim Biophys Acta. 2013. PMID: 23567938 Free article.

2

IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis.

Murphy M, Docherty NG, Griffin B, Howlin J, McArdle E, McMahon R, Schmid H, Kretzler M, Droguett A, Mezzano S, Brady HR, Furlong F, Godson C, Martin F. Murphy M, et al. J Am Soc Nephrol. 2008 Sep;19(9):1672-80. doi: 10.1681/ASN.2007101080. Epub 2008 May 28. J Am Soc Nephrol. 2008. PMID: 18508967 Free PMC article.

3

IHG-1 amplifies TGF-β1 signalling and mitochondrial biogenesis and is increased in diabetic kidney disease.

Murphy M, Hickey F, Godson C. Murphy M, et al. Curr Opin Nephrol Hypertens. 2013 Jan;22(1):77-84. doi: 10.1097/MNH.0b013e32835b54b0. Curr Opin Nephrol Hypertens. 2013. PMID: 23165112 Review.

4

IHG-1 increases mitochondrial fusion and bioenergetic function.

Hickey FB, Corcoran JB, Griffin B, Bhreathnach U, Mortiboys H, Reid HM, Andrews D, Byrne S, Furlong F, Martin F, Godson C, Murphy M. Hickey FB, et al. Among authors: murphy m. Diabetes. 2014 Dec;63(12):4314-25. doi: 10.2337/db13-1256. Epub 2014 Jul 9. Diabetes. 2014. PMID: 25008184

5

Targeting cellular drivers and counter-regulators of hyperglycaemia- and transforming growth factor-β1-associated profibrotic responses in diabetic kidney disease.

Docherty NG, Murphy M, Martin F, Brennan EP, Godson C. Docherty NG, et al. Among authors: murphy m. Exp Physiol. 2014 Sep;99(9):1154-62. doi: 10.1113/expphysiol.2014.078774. Epub 2014 Aug 1. Exp Physiol. 2014. PMID: 25085843 Free article. Review.

6

Profibrotic IHG-1 complexes with renal disease associated HSPA5 and TRAP1 in mitochondria.

Bhreathnach U, Griffin B, Brennan E, Ewart L, Higgins D, Murphy M. Bhreathnach U, et al. Among authors: murphy m. Biochim Biophys Acta Mol Basis Dis. 2017 Apr;1863(4):896-906. doi: 10.1016/j.bbadis.2017.01.015. Epub 2017 Jan 20. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 28115289 Free article.

7

The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells.

Crean JK, Finlay D, Murphy M, Moss C, Godson C, Martin F, Brady HR. Crean JK, et al. Among authors: murphy m. J Biol Chem. 2002 Nov 15;277(46):44187-94. doi: 10.1074/jbc.M203715200. Epub 2002 Sep 5. J Biol Chem. 2002. PMID: 12218048 Free article.

8

Dysregulated intracellular signaling impairs CTGF-stimulated responses in human mesangial cells exposed to high extracellular glucose.

Furlong F, Crean J, Thornton L, O'Leary R, Murphy M, Martin F. Furlong F, et al. Among authors: murphy m. Am J Physiol Renal Physiol. 2007 Jun;292(6):F1691-700. doi: 10.1152/ajprenal.00342.2006. Epub 2007 Feb 27. Am J Physiol Renal Physiol. 2007. PMID: 17327498 Free article.

9

Regulation and consequences of differential gene expression in diabetic kidney disease.

Murphy M, Crean J, Brazil DP, Sadlier D, Martin F, Godson C. Murphy M, et al. Biochem Soc Trans. 2008 Oct;36(Pt 5):941-5. doi: 10.1042/BST0360941. Biochem Soc Trans. 2008. PMID: 18793165

10

Lipoxin A₄ and benzo-lipoxin A₄ attenuate experimental renal fibrosis.

Börgeson E, Docherty NG, Murphy M, Rodgers K, Ryan A, O'Sullivan TP, Guiry PJ, Goldschmeding R, Higgins DF, Godson C. Börgeson E, et al. Among authors: murphy m. FASEB J. 2011 Sep;25(9):2967-79. doi: 10.1096/fj.11-185017. Epub 2011 May 31. FASEB J. 2011. PMID: 21628447

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