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Development of the Inhibitors that Target the PD-1/PD-L1 Interaction-A Brief Look at Progress on Small Molecules, Peptides and Macrocycles.
Molecules. 2019 May 30;24(11):2071. doi: 10.3390/molecules24112071.
Molecules. 2019.
PMID: 31151293
Free PMC article.
Review.
Hitting on the move: Targeting intrinsically disordered protein states of the MDM2-p53 interaction.
Neochoritis CG, Atmaj J, Twarda-Clapa A, Surmiak E, Skalniak L, Köhler LM, Muszak D, Kurpiewska K, Kalinowska-Tłuścik J, Beck B, Holak TA, Dömling A.
Neochoritis CG, et al. Among authors: muszak d.
Eur J Med Chem. 2019 Nov 15;182:111588. doi: 10.1016/j.ejmech.2019.111588. Epub 2019 Aug 6.
Eur J Med Chem. 2019.
PMID: 31421630
Free PMC article.
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Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction.
Muszak D, Surmiak E, Plewka J, Magiera-Mularz K, Kocik-Krol J, Musielak B, Sala D, Kitel R, Stec M, Weglarczyk K, Siedlar M, Dömling A, Skalniak L, Holak TA.
Muszak D, et al.
J Med Chem. 2021 Aug 12;64(15):11614-11636. doi: 10.1021/acs.jmedchem.1c00957. Epub 2021 Jul 27.
J Med Chem. 2021.
PMID: 34313116
Free PMC article.
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PD-L1 Inhibitors: Different Classes, Activities, and Mechanisms of Action.
Surmiak E, Magiera-Mularz K, Musielak B, Muszak D, Kocik-Krol J, Kitel R, Plewka J, Holak TA, Skalniak L.
Surmiak E, et al. Among authors: muszak d.
Int J Mol Sci. 2021 Oct 30;22(21):11797. doi: 10.3390/ijms222111797.
Int J Mol Sci. 2021.
PMID: 34769226
Free PMC article.
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Exploring the Surface of the Ectodomain of the PD-L1 Immune Checkpoint with Small-Molecule Fragments.
Kitel R, Rodríguez I, Del Corte X, Atmaj J, Żarnik M, Surmiak E, Muszak D, Magiera-Mularz K, Popowicz GM, Holak TA, Musielak B.
Kitel R, et al. Among authors: muszak d.
ACS Chem Biol. 2022 Sep 16;17(9):2655-2663. doi: 10.1021/acschembio.2c00583. Epub 2022 Sep 8.
ACS Chem Biol. 2022.
PMID: 36073782
Free PMC article.
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Solubilizer Tag Effect on PD-L1/Inhibitor Binding Properties for m-Terphenyl Derivatives.
Surmiak E, Ząber J, Plewka J, Wojtanowicz G, Kocik-Krol J, Kruc O, Muszak D, Rodríguez I, Musielak B, Viviano M, Castellano S, Skalniak L, Magiera-Mularz K, Holak TA, Kalinowska-Tłuścik J.
Surmiak E, et al. Among authors: muszak d.
ACS Med Chem Lett. 2023 Dec 14;15(1):36-44. doi: 10.1021/acsmedchemlett.3c00306. eCollection 2024 Jan 11.
ACS Med Chem Lett. 2023.
PMID: 38229762
Free PMC article.
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