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Page 1
Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants.
Mannan A, Muhsen IN, Barragán E, Sanz MA, Mohty M, Hashmi SK, Aljurf M. Mannan A, et al. Hematol Oncol Stem Cell Ther. 2020 Dec;13(4):189-201. doi: 10.1016/j.hemonc.2020.05.007. Epub 2020 May 20. Hematol Oncol Stem Cell Ther. 2020. PMID: 32473106 Free article. Review.
Reviewed genes involved in APL variants include: ZBTB16, NPM, NuMA, STAT5b, PRKAR1A, FIP1L1, BCOR, NABP1, TBLR1, GTF2I, IRF2BP2, FNDC3B, ADAMDTS17, STAT3, and TFG. ...
Reviewed genes involved in APL variants include: ZBTB16, NPM, NuMA, STAT5b, PRKAR1A, FIP1L1, BCOR, NABP1, TBLR1, GTF2I, IRF2BP2, FNDC …
Transcriptionally regulated miR-26a-5p may act as BRCAness in Triple-Negative Breast Cancer.
Zhang Y, Lv L, Zheng R, Xie R, Yu Y, Liao H, Chen J, Zhang B. Zhang Y, et al. Breast Cancer Res. 2023 Jun 26;25(1):75. doi: 10.1186/s13058-023-01663-y. Breast Cancer Res. 2023. PMID: 37365643 Free PMC article.
BACKGROUND: DNA damage and DNA damage repair (DDR) are important therapeutic targets for triple-negative breast cancer (TNBC), a subtype with limited chemotherapy efficiency and poor outcome. ...Besides, miR-26a-5p negatively regulated the expression of BARD1 and NABP1 …
BACKGROUND: DNA damage and DNA damage repair (DDR) are important therapeutic targets for triple-negative breast cancer (TNBC), a subt …
hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage.
Boucher D, Kariawasam R, Burgess J, Gimenez A, Ocampo TE, Ferguson B, Naqi A, Walker GJ, Bolderson E, Gamsjaeger R, O'Byrne KJ, Cubeddu L, Khanna KK, Richard DJ. Boucher D, et al. Sci Rep. 2021 Oct 12;11(1):20256. doi: 10.1038/s41598-021-99355-0. Sci Rep. 2021. PMID: 34642383 Free PMC article.
Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic cells have multiple pathways to efficiently detect, signal and repair DNA damage. ...
Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic cells have multiple pathways to …
The structural details of the interaction of single-stranded DNA binding protein hSSB2 (NABP1/OBFC2A) with UV-damaged DNA.
Lawson T, El-Kamand S, Boucher D, Duong DC, Kariawasam R, Bonvin AMJJ, Richard DJ, Gamsjaeger R, Cubeddu L. Lawson T, et al. Proteins. 2020 Feb;88(2):319-326. doi: 10.1002/prot.25806. Epub 2019 Aug 30. Proteins. 2020. PMID: 31443132
While a wealth of structural and functional data is available on the essential human SSB, hSSB1 (NABP2/OBFC2B), the close homolog hSSB2 (NABP1/OBFC2A) remains relatively uncharacterized. Both SSBs possess a well-structured OB (oligonucleotide/oligosaccharide-binding) domai …
While a wealth of structural and functional data is available on the essential human SSB, hSSB1 (NABP2/OBFC2B), the close homolog hSSB2 ( …
DIRC3 and near NABP1 genetic polymorphisms are associated laryngeal squamous cell carcinoma patient survival.
Shen Z, Ren W, Bai Y, Chen Z, Li J, Li B, Jin T, Cao P, Shao Y. Shen Z, et al. Oncotarget. 2016 Nov 29;7(48):79596-79604. doi: 10.18632/oncotarget.12865. Oncotarget. 2016. PMID: 27793000 Free PMC article.
We found that the single nucleotide polymorphisms (SNPs), rs11903757, with closest proximity to NABP1 and SDPR, and rs966423 in DIRC3, were associated with survival in LSCC patients. ...
We found that the single nucleotide polymorphisms (SNPs), rs11903757, with closest proximity to NABP1 and SDPR, and rs966423 in DIRC3 …
The Integrator complex controls the termination of transcription at diverse classes of gene targets.
Skaar JR, Ferris AL, Wu X, Saraf A, Khanna KK, Florens L, Washburn MP, Hughes SH, Pagano M. Skaar JR, et al. Cell Res. 2015 Mar;25(3):288-305. doi: 10.1038/cr.2015.19. Epub 2015 Feb 13. Cell Res. 2015. PMID: 25675981 Free PMC article.
Complexes containing INTS3 and either NABP1 or NABP2 were initially characterized in DNA damage responses, but their biochemical function remained unknown. ...
Complexes containing INTS3 and either NABP1 or NABP2 were initially characterized in DNA damage responses, but their biochemical func …