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Year Number of Results
2011 3
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NCAPD2 inhibits autophagy by regulating Ca(2+)/CAMKK2/AMPK/mTORC1 pathway and PARP-1/SIRT1 axis to promote colorectal cancer.
Jing Z, He X, Jia Z, Sa Y, Yang B, Liu P. Jing Z, et al. Cancer Lett. 2021 Nov 1;520:26-37. doi: 10.1016/j.canlet.2021.06.029. Epub 2021 Jul 3. Cancer Lett. 2021. PMID: 34229059
NCAPD2 acts as a tumor promoter both in vitro and in vivo. NCAPD2 knockout suppresses colorectal cancer development in AOM/DSS induced mice model. Therefore, our findings support a role for NCAPD2 in autophagy to promote CRC development and highlight …
NCAPD2 acts as a tumor promoter both in vitro and in vivo. NCAPD2 knockout suppresses colorectal cancer development in …
NCAPD2 promotes breast cancer progression through E2F1 transcriptional regulation of CDK1.
He J, Gao R, Yang J, Li F, Fu Y, Cui J, Liu X, Huang K, Guo Q, Zhou Z, Wei W. He J, et al. Cancer Sci. 2023 Mar;114(3):896-907. doi: 10.1111/cas.15347. Epub 2022 Dec 25. Cancer Sci. 2023. PMID: 35348268 Free PMC article.
Breast cancer (BC) is a serious threat to women's health worldwide. Non-SMC condensin I complex subunit D2 (NCAPD2) is a regulatory subunit of the coagulin I complex, which is mainly involved in chromosome coagulation and separation. ...It was further confirmed that …
Breast cancer (BC) is a serious threat to women's health worldwide. Non-SMC condensin I complex subunit D2 (NCAPD2) is a regul …
Non-SMC condensin I complex subunit D2 (NCAPD2) reveals its prognostic and immunologic features in human cancers.
Dong X, Liu T, Li Z, Zhai Y. Dong X, et al. Aging (Albany NY). 2023 Jul 26;15(14):7237-7257. doi: 10.18632/aging.204904. Epub 2023 Jul 26. Aging (Albany NY). 2023. PMID: 37498296 Free PMC article.
Non-SMC condensin I complex subunit D2 (NCAPD2) is overexpressed in some malignant tumors. However, there are few studies on the function of NCAPD2 in pan-cancer. ...NCAPD2 may act as a prognostic molecular marker in most cancers....
Non-SMC condensin I complex subunit D2 (NCAPD2) is overexpressed in some malignant tumors. However, there are few studies on the func …
NCAPD2 is a novel marker for the poor prognosis of lung adenocarcinoma and is associated with immune infiltration and tumor mutational burden.
Li Z, Zheng Y, Wu Z, Zhuo T, Zhu Y, Dai L, Wang Y, Chen M. Li Z, et al. Medicine (Baltimore). 2023 Jan 20;102(3):e32686. doi: 10.1097/MD.0000000000032686. Medicine (Baltimore). 2023. PMID: 36701707 Free PMC article.
Lung adenocarcinoma (LUAD) is at present the most prevalent subtype of lung cancer worldwide. Non-SMC condensin I complex subunit D2 (NCAPD2) is one of the 3 non-SMC subunits in condensin I. ...We investigated differences in the expression levels of NCAPD2 an …
Lung adenocarcinoma (LUAD) is at present the most prevalent subtype of lung cancer worldwide. Non-SMC condensin I complex subunit D2 …
Non-SMC Condensin I Complex Subunit D2 Is a Prognostic Factor in Triple-Negative Breast Cancer for the Ability to Promote Cell Cycle and Enhance Invasion.
Zhang Y, Liu F, Zhang C, Ren M, Kuang M, Xiao T, Di X, Feng L, Fu L, Cheng S. Zhang Y, et al. Am J Pathol. 2020 Jan;190(1):37-47. doi: 10.1016/j.ajpath.2019.09.014. Epub 2019 Oct 12. Am J Pathol. 2020. PMID: 31610177 Free article.
The role of non-SMC condensin I complex subunit D2 (NCAPD2), a regulatory subunit of the condensin I complex that mainly participates in chromosome condensation and segregation, has not been reported in cancer. ...For the first time, we report the close association …
The role of non-SMC condensin I complex subunit D2 (NCAPD2), a regulatory subunit of the condensin I complex that mainly participates …
NCPAD2 is a favorable predictor of prognostic and immunotherapeutic biomarker for multiple cancer types including lung cancer.
Feng L, Yang Y, Lin Z, Cui M, Jin A, Cui A. Feng L, et al. Genes Environ. 2024 Jan 3;46(1):2. doi: 10.1186/s41021-023-00291-4. Genes Environ. 2024. PMID: 38172945 Free PMC article.
While the different contribution of NCAPD2 to chromosome in mitosis have been thoroughly investigated, much less is known about the expression of NCAPD2 in pan-cancer. ...CONCLUSIONS: It was found that NCAPD2 was overexpressed in pan-cancers, wh …
While the different contribution of NCAPD2 to chromosome in mitosis have been thoroughly investigated, much less is known about the e …
NCAPD2 promotes the malignant progression of oral squamous cell carcinoma via the Wnt/beta-catenin pathway.
Ma P, Yu H, Zhu M, Liu L, Cheng L, Han Z, Jin W. Ma P, et al. Cell Cycle. 2024 Mar;23(5):588-601. doi: 10.1080/15384101.2024.2348918. Epub 2024 May 14. Cell Cycle. 2024. PMID: 38743408 Free PMC article.
In vitro, the knockdown of NCAPD2 inhibited OSCC cell proliferation and promoted apoptosis. NCAPD2 depletion also significantly inhibited the migration of OSCC cells. ...In vivo, we demonstrated that downregulating NCAPD2 could inhibit the tumorigenicity of O …
In vitro, the knockdown of NCAPD2 inhibited OSCC cell proliferation and promoted apoptosis. NCAPD2 depletion also significantl …
Identification of circRNA-miRNA-mRNA regulatory network in gastric cancer by analysis of microarray data.
Guan YJ, Ma JY, Song W. Guan YJ, et al. Cancer Cell Int. 2019 Jul 16;19:183. doi: 10.1186/s12935-019-0905-z. eCollection 2019. Cancer Cell Int. 2019. PMID: 31346318 Free PMC article.
BACKGROUND: Evidence is increasingly indicating that circular RNAs (circRNAs) are closely involved in tumorigenesis and cancer progression. However, the function of circRNAs in gastric cancer (GC) are still unknown. ...A PPI network was established and four hub gene …
BACKGROUND: Evidence is increasingly indicating that circular RNAs (circRNAs) are closely involved in tumorigenesis and cancer progre …
High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/beta-catenin signaling pathway in HCC.
Mai Y, Liao C, Wang S, Zhou X, Meng L, Chen C, Qin Y, Deng G. Mai Y, et al. Am J Cancer Res. 2024 Apr 15;14(4):1685-1711. doi: 10.62347/HYNZ9211. eCollection 2024. Am J Cancer Res. 2024. PMID: 38726276 Free PMC article.
In vitro experiments demonstrated that high glucose upregulated NCAPD2 expression, enhancing proliferation, invasion, and EMT, while knockdown of NCAPD2 reversed these effects. ...Additionally, NCAPD2 was positively correlated with EMT and the Wnt/beta-cateni …
In vitro experiments demonstrated that high glucose upregulated NCAPD2 expression, enhancing proliferation, invasion, and EMT, while …
15 results