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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1998 11
1999 6
2000 6
2001 9
2002 12
2003 13
2004 15
2005 12
2006 15
2007 19
2008 9
2009 11
2010 10
2011 15
2012 12
2013 20
2014 7
2015 14
2016 17
2017 12
2018 9
2019 15
2020 19
2021 22
2022 17
2023 20
2024 5

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323 results

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Page 1
NCOR1 Sustains Colorectal Cancer Cell Growth and Protects against Cellular Senescence.
St-Jean S, De Castro AC, Lecours M, Jones C, Rivard N, Rodier F, Perreault N, Boudreau F. St-Jean S, et al. Cancers (Basel). 2021 Sep 1;13(17):4414. doi: 10.3390/cancers13174414. Cancers (Basel). 2021. PMID: 34503224 Free PMC article.
We hypothesized that NCOR1 could control colorectal cancer cell proliferation and tumorigenicity. ...The acquisition of a pro-metastasis signature in the absence of NCOR1 could indicate long-term potential adverse consequences of colon-cancer-induced s …
We hypothesized that NCOR1 could control colorectal cancer cell proliferation and tumorigenicity. ...The acquisition of a pro- …
Breast cancer plasticity is restricted by a LATS1-NCOR1 repressive axis.
Aylon Y, Furth N, Mallel G, Friedlander G, Nataraj NB, Dong M, Hassin O, Zoabi R, Cohen B, Drendel V, Salame TM, Mukherjee S, Harpaz N, Johnson R, Aulitzky WE, Yarden Y, Shema E, Oren M. Aylon Y, et al. Nat Commun. 2022 Nov 28;13(1):7199. doi: 10.1038/s41467-022-34863-9. Nat Commun. 2022. PMID: 36443319 Free PMC article.
Breast cancer, the most frequent cancer in women, is generally classified into several distinct histological and molecular subtypes. ...We propose that by enforcing rigorous silencing of repressed genes, the LATS1-NCOR1 axis maintains luminal cell identity an …
Breast cancer, the most frequent cancer in women, is generally classified into several distinct histological and molecular sub …
The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
Chang S, Yim S, Park H. Chang S, et al. Exp Mol Med. 2019 Jun 20;51(6):1-17. doi: 10.1038/s12276-019-0230-6. Exp Mol Med. 2019. PMID: 31221981 Free PMC article. Review.
Recent studies on mutations in cancer genomes have distinguished driver mutations from passenger mutations, which occur as byproducts of cancer development. The cancer genome atlas (TCGA) project identified 299 genes and 24 pathways/biological processes that …
Recent studies on mutations in cancer genomes have distinguished driver mutations from passenger mutations, which occur as byproducts …
Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Lymph Node Metastasis of Bladder Cancer.
An M, Zheng H, Huang J, Lin Y, Luo Y, Kong Y, Pang M, Zhang D, Yang J, Chen J, Li Y, Chen C, Lin T. An M, et al. Cancer Res. 2022 Jun 15;82(12):2239-2253. doi: 10.1158/0008-5472.CAN-21-4349. Cancer Res. 2022. PMID: 35395674 Free PMC article.
Dysregulation of cellular homeostasis can drive their nuclear export, which may be involved in cancer metastasis. However, the mechanism underlying circRNA nuclear export and its role in lymph node (LN) metastasis of bladder cancer remain unclear. ...This study high …
Dysregulation of cellular homeostasis can drive their nuclear export, which may be involved in cancer metastasis. However, the mechan …
Genomic characterization of metastatic breast cancers.
Bertucci F, Ng CKY, Patsouris A, Droin N, Piscuoglio S, Carbuccia N, Soria JC, Dien AT, Adnani Y, Kamal M, Garnier S, Meurice G, Jimenez M, Dogan S, Verret B, Chaffanet M, Bachelot T, Campone M, Lefeuvre C, Bonnefoi H, Dalenc F, Jacquet A, De Filippo MR, Babbar N, Birnbaum D, Filleron T, Le Tourneau C, André F. Bertucci F, et al. Nature. 2019 May;569(7757):560-564. doi: 10.1038/s41586-019-1056-z. Epub 2019 May 22. Nature. 2019. PMID: 31118521
Here we investigated the landscape of somatic alterations in 617 metastatic breast cancers. Nine driver genes (TP53, ESR1, GATA3, KMT2C, NCOR1, AKT1, NF1, RIC8A and RB1) were more frequently mutated in metastatic breast cancers that expressed hormone receptor …
Here we investigated the landscape of somatic alterations in 617 metastatic breast cancers. Nine driver genes (TP53, ESR1, GATA3, KMT …
HPV16 E6-Activated OCT4 Promotes Cervical Cancer Progression by Suppressing p53 Expression via Co-Repressor NCOR1.
Shu S, Li Z, Liu L, Ying X, Zhang Y, Wang T, Zhou X, Jiang P, Lv W. Shu S, et al. Front Oncol. 2022 Jul 7;12:900856. doi: 10.3389/fonc.2022.900856. eCollection 2022. Front Oncol. 2022. PMID: 35875100 Free PMC article.
Cervical cancer patients with higher levels of OCT4 had worse survival rates. ...In conclusion, our results suggested that HPV16 E6 activated the expression of OCT4 and subsequently crippled the transcription of p53 via co-repressor NCOR1, which contributed to cervi …
Cervical cancer patients with higher levels of OCT4 had worse survival rates. ...In conclusion, our results suggested that HPV16 E6 a …
TNFalpha Enhances Tamoxifen Sensitivity through Dissociation of ERalpha-p53-NCOR1 Complexes in ERalpha-Positive Breast Cancer.
Kim H, Park SH, Lee J, Sung GJ, Song JH, Kwak S, Jeong JH, Kong MJ, Hwang JT, Choi HK, Choi KC. Kim H, et al. Cancers (Basel). 2021 May 26;13(11):2601. doi: 10.3390/cancers13112601. Cancers (Basel). 2021. PMID: 34073371 Free PMC article.
Moreover, knockdown of NCOR1, similar to TNFalpha treatment, suppressed cancer cell growth and promoted apoptosis only in MCF7 cells and MCF7 xenograft mice through the stabilization of p53, a tumor suppressor protein. ...In conclusion, TNFalpha promoted tamoxifen s …
Moreover, knockdown of NCOR1, similar to TNFalpha treatment, suppressed cancer cell growth and promoted apoptosis only in MCF7 …
Author Correction: Breast cancer plasticity is restricted by a LATS1-NCOR1 repressive axis.
Aylon Y, Furth N, Mallel G, Friedlander G, Nataraj NB, Dong M, Hassin O, Zoabi R, Cohen B, Drendel V, Salame TM, Mukherjee S, Harpaz N, Johnson R, Aulitzky WE, Yarden Y, Shema E, Oren M. Aylon Y, et al. Nat Commun. 2023 Jan 10;14(1):133. doi: 10.1038/s41467-023-35838-0. Nat Commun. 2023. PMID: 36627302 Free PMC article. No abstract available.
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Hogg SJ, Motorna O, Cluse LA, Johanson TM, Coughlan HD, Raviram R, Myers RM, Costacurta M, Todorovski I, Pijpers L, Bjelosevic S, Williams T, Huskins SN, Kearney CJ, Devlin JR, Fan Z, Jabbari JS, Martin BP, Fareh M, Kelly MJ, Dupéré-Richer D, Sandow JJ, Feran B, Knight D, Khong T, Spencer A, Harrison SJ, Gregory G, Wickramasinghe VO, Webb AI, Taberlay PC, Bromberg KD, Lai A, Papenfuss AT, Smyth GK, Allan RS, Licht JD, Landau DA, Abdel-Wahab O, Shortt J, Vervoort SJ, Johnstone RW. Hogg SJ, et al. Mol Cell. 2021 May 20;81(10):2183-2200.e13. doi: 10.1016/j.molcel.2021.04.015. Mol Cell. 2021. PMID: 34019788 Free PMC article.
We found that catalytic P300/CBP inhibition dynamically perturbs steady-state acetylation kinetics and suppresses oncogenic transcriptional networks in the absence of changes to chromatin accessibility. CRISPR-Cas9 screening identified NCOR1 and HDAC3 transcriptional co-re …
We found that catalytic P300/CBP inhibition dynamically perturbs steady-state acetylation kinetics and suppresses oncogenic transcriptional …
Abnormally localized DLK1 interacts with NCOR1 in non-small cell lung cancer cell nuclear.
Tan J, Zhang S, Li L, Mu J, Wang Z, Zhang L, Jiang M, Li W, Yang X, Liu Y, Gao Y. Tan J, et al. Biosci Rep. 2019 Dec 20;39(12):BSR20192362. doi: 10.1042/BSR20192362. Biosci Rep. 2019. PMID: 31661545 Free PMC article.
We analyzed the expression of NCOR1 in two independent cohorts and demonstrated that NCOR1 is a tumor suppressor and has prognosis potential in lung squamous carcinomas. At last, we analyzed the colocalization of DLK1 and NCOR1 in 147 NSCLC samples by immunoh …
We analyzed the expression of NCOR1 in two independent cohorts and demonstrated that NCOR1 is a tumor suppressor and has progn …
323 results