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Year Number of Results
1992 1
1993 4
1994 5
1995 4
1996 2
1997 3
2000 2
2003 3
2004 1
2005 2
2006 6
2007 7
2008 2
2009 1
2010 5
2011 6
2012 10
2013 11
2014 15
2015 22
2016 20
2017 13
2018 12
2019 14
2020 22
2021 13
2022 13
2023 11
2024 4

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205 results

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Page 1
Cancer-Associated Fibroblast-Induced Remodeling of Tumor Microenvironment in Recurrent Bladder Cancer.
Liang T, Tao T, Wu K, Liu L, Xu W, Zhou D, Fang H, Ding Q, Huang G, Wu S. Liang T, et al. Adv Sci (Weinh). 2023 Nov;10(31):e2303230. doi: 10.1002/advs.202303230. Epub 2023 Sep 24. Adv Sci (Weinh). 2023. PMID: 37743226 Free PMC article.
However, the relationship between individual TME components, particularly cancer-associated fibroblasts (CAFs), and tumor recurrence is unclear. ...ICAM1+ iCAFs are found to secrete CCL2, which binds to CCR2 in MDSCs. Moreover, elevated STAT3, NFKB2, VEGFA, and CTGF …
However, the relationship between individual TME components, particularly cancer-associated fibroblasts (CAFs), and tumor recurrence …
Comprehensive molecular phenotyping of ARID1A-deficient gastric cancer reveals pervasive epigenomic reprogramming and therapeutic opportunities.
Xu C, Huang KK, Law JH, Chua JS, Sheng T, Flores NM, Pizzi MP, Okabe A, Tan ALK, Zhu F, Kumar V, Lu X, Benitez AM, Lian BSX, Ma H, Ho SWT, Ramnarayanan K, Anene-Nzelu CG, Razavi-Mohseni M, Abdul Ghani SAB, Tay ST, Ong X, Lee MH, Guo YA, Ashktorab H, Smoot D, Li S, Skanderup AJ, Beer MA, Foo RSY, Wong JSH, Sanghvi K, Yong WP, Sundar R, Kaneda A, Prabhakar S, Mazur PK, Ajani JA, Yeoh KG, So JB, Tan P; Singapore Gastric Cancer Consortium. Xu C, et al. Gut. 2023 Sep;72(9):1651-1663. doi: 10.1136/gutjnl-2022-328332. Epub 2023 Mar 14. Gut. 2023. PMID: 36918265
OBJECTIVE: Gastric cancer (GC) is a leading cause of cancer mortality, with ARID1A being the second most frequently mutated driver gene in GC. ...CONCLUSION: Our results suggest a therapeutic strategy for ARID1A-mutated GCs targeting both tumour-intrinsic (BRD4-asso …
OBJECTIVE: Gastric cancer (GC) is a leading cause of cancer mortality, with ARID1A being the second most frequently mutated dr …
NFKB2 gene expression in patients with peptic ulcer diseases and gastric cancer.
Marta ŻN, Agnieszka W, Jacek P, Jeleń A, Adrian K, Dagmara SK, Sałagacka-Kubiak A, Balcerczak E. Marta ŻN, et al. Mol Biol Rep. 2020 Mar;47(3):2015-2021. doi: 10.1007/s11033-020-05299-5. Epub 2020 Feb 13. Mol Biol Rep. 2020. PMID: 32056043
RNA was isolated from: 79 samples of peptic ulcer, 22 gastric cancer and 11 control tissue. The real-time PCR technique was used to study the expression of NFKB2 gene. ...Peptic ulcer cases showed the increased relative NFKB2 gene expression to control group …
RNA was isolated from: 79 samples of peptic ulcer, 22 gastric cancer and 11 control tissue. The real-time PCR technique was used to s …
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
Mueller S, Engleitner T, Maresch R, Zukowska M, Lange S, Kaltenbacher T, Konukiewitz B, Öllinger R, Zwiebel M, Strong A, Yen HY, Banerjee R, Louzada S, Fu B, Seidler B, Götzfried J, Schuck K, Hassan Z, Arbeiter A, Schönhuber N, Klein S, Veltkamp C, Friedrich M, Rad L, Barenboim M, Ziegenhain C, Hess J, Dovey OM, Eser S, Parekh S, Constantino-Casas F, de la Rosa J, Sierra MI, Fraga M, Mayerle J, Klöppel G, Cadiñanos J, Liu P, Vassiliou G, Weichert W, Steiger K, Enard W, Schmid RM, Yang F, Unger K, Schneider G, Varela I, Bradley A, Saur D, Rad R. Mueller S, et al. Nature. 2018 Feb 1;554(7690):62-68. doi: 10.1038/nature25459. Epub 2018 Jan 24. Nature. 2018. PMID: 29364867 Free PMC article.
Integration of cell culture genomes, transcriptomes and tumour phenotypes with functional studies and human data reveals additional widespread effects of oncogenic dosage variation on cell morphology and plasticity, histopathology and clinical outcome, with the highest Kras(MUT) …
Integration of cell culture genomes, transcriptomes and tumour phenotypes with functional studies and human data reveals additional widespre …
NFKB2 mediates colorectal cancer cell immune escape and metastasis in a STAT2/PD‐L1‐dependent manner.
Zhang J, Ma F, Li Z, Li Y, Sun X, Song M, Yang F, Wu E, Wei X, Wang Z, Yang L. Zhang J, et al. MedComm (2020). 2024 Apr 24;5(5):e521. doi: 10.1002/mco2.521. eCollection 2024 May. MedComm (2020). 2024. PMID: 38660687 Free PMC article. Catalan.
This study systematically analyzed the molecular mechanism and function of nuclear factor kappa B subunit 2 (NFKB2) in colorectal cancer (CRC) to investigate the potential of NFKB2 as a therapeutic target for CRC. ...In conclusion, the facilitated NFKB2 …
This study systematically analyzed the molecular mechanism and function of nuclear factor kappa B subunit 2 (NFKB2) in colorectal …
Nasopharyngeal carcinoma cells promote regulatory T cell development and suppressive activity via CD70-CD27 interaction.
Gong L, Luo J, Zhang Y, Yang Y, Li S, Fang X, Zhang B, Huang J, Chow LK, Chung D, Huang J, Huang C, Liu Q, Bai L, Tiu YC, Wu P, Wang Y, Tsao GS, Kwong DL, Lee AW, Dai W, Guan XY. Gong L, et al. Nat Commun. 2023 Apr 6;14(1):1912. doi: 10.1038/s41467-023-37614-6. Nat Commun. 2023. PMID: 37024479 Free PMC article.
Furthermore, ATAC-Seq delineates that CD70 is transcriptionally upregulated by NFKB2 via an Epstein-Barr virus-dependent epigenetic modification. ...
Furthermore, ATAC-Seq delineates that CD70 is transcriptionally upregulated by NFKB2 via an Epstein-Barr virus-dependent epigenetic m …
Altered mRNA Expression of NFKB1 and NFKB2 Genes in Penile Lichen Sclerosus, Penile Cancer and Zoon Balanitis.
Wierzbicki PM, Czajkowski M, Kotulak-Chrząszcz A, Bukowicz J, Dzieciuch K, Sokołowska-Wojdyło M, Kmieć Z, Matuszewski M. Wierzbicki PM, et al. J Clin Med. 2022 Dec 7;11(24):7254. doi: 10.3390/jcm11247254. J Clin Med. 2022. PMID: 36555871 Free PMC article.
BACKGROUND: The nuclear factor-kappaB transcription factors 1 and 2 (NFKB1 and NFKB2) are key components of the NF-kappaB pathway, which responds to inflammatory signals. ...NFKB1/2 mRNA levels were quantified by qPCR. RESULTS: The highest levels of NFKB1 and NFKB2 …
BACKGROUND: The nuclear factor-kappaB transcription factors 1 and 2 (NFKB1 and NFKB2) are key components of the NF-kappaB pathway, wh …
Important role of Nfkb2 in the Kras(G12D)-driven carcinogenesis in the pancreas.
Hassan Z, Schneeweis C, Wirth M, Müller S, Geismann C, Neuß T, Steiger K, Krämer OH, Schmid RM, Rad R, Arlt A, Reichert M, Saur D, Schneider G. Hassan Z, et al. Pancreatology. 2021 Aug;21(5):912-919. doi: 10.1016/j.pan.2021.03.012. Epub 2021 Mar 26. Pancreatology. 2021. PMID: 33824054 Free article.
Although recent evidence has shown that oncogenic gains in Nfkappab2 collaborate with Kras in the carcinogenesis, no data at the level of genetics for the contribution of Nfkappab2 is available so far. METHODS: We used Nfkb2 knock-out mice to decipher the role of the gene …
Although recent evidence has shown that oncogenic gains in Nfkappab2 collaborate with Kras in the carcinogenesis, no data at the level of ge …
BET inhibitor suppresses melanoma progression via the noncanonical NF-κB/SPP1 pathway.
Deng G, Zeng F, Su J, Zhao S, Hu R, Zhu W, Hu S, Chen X, Yin M. Deng G, et al. Theranostics. 2020 Sep 15;10(25):11428-11443. doi: 10.7150/thno.47432. eCollection 2020. Theranostics. 2020. PMID: 33052224 Free PMC article.
Notably, BRD4 did not bind directly to the SPP1 promoter but regulated SPP1 expression through NFKB2. Silencing of NFKB2 resembled the phenotype of BET inhibitors treatment and SPP1 silencing in melanoma. ...
Notably, BRD4 did not bind directly to the SPP1 promoter but regulated SPP1 expression through NFKB2. Silencing of NFKB2 resem …
ECCR1 and NFKB2 Polymorphisms as Potential Biomarkers of Non-small Cell Lung Cancer in a Polish Population.
Chaszczewska-Markowska M, Kosacka M, Chryplewicz A, Dyła T, Brzecka A, Bogunia-Kubik K. Chaszczewska-Markowska M, et al. Anticancer Res. 2019 Jun;39(6):3269-3272. doi: 10.21873/anticanres.13469. Anticancer Res. 2019. PMID: 31177178
We, therefore, performed a case-control study to investigate the association of seven selected single nucleotide polymorphisms (SNPs), in genes coding for excision repair cross-complimentary group 1 (ERCC1: rs11615, rs3212986, rs2298881), nuclear factor qB (NFKB2: rs789794 …
We, therefore, performed a case-control study to investigate the association of seven selected single nucleotide polymorphisms (SNPs), in ge …
205 results