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Neurotrophic actions initiated by proNGF in adult sensory neurons may require peri-somatic glia to drive local cleavage to NGF.
J Neurochem. 2012 Aug;122(3):523-36. doi: 10.1111/j.1471-4159.2012.07799.x. Epub 2012 Jun 12.
J Neurochem. 2012.
PMID: 22621370
Free PMC article.
Dissecting the diverse actions of pro- and mature neurotrophins.
Hempstead BL.
Hempstead BL.
Curr Alzheimer Res. 2006 Feb;3(1):19-24. doi: 10.2174/156720506775697061.
Curr Alzheimer Res. 2006.
PMID: 16472198
Review.
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Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.
Pedraza CE, Podlesniy P, Vidal N, Arévalo JC, Lee R, Hempstead B, Ferrer I, Iglesias M, Espinet C.
Pedraza CE, et al.
Am J Pathol. 2005 Feb;166(2):533-43. doi: 10.1016/S0002-9440(10)62275-4.
Am J Pathol. 2005.
PMID: 15681836
Free PMC article.
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Dissociation of NGF induced signal transduction from neurite elongation by expression of a mutant adaptor protein v-Crk in PC12 cells.
Teng KK, Courtney JC, van Bergen en Henegouwen P, Birge RB, Hempstead BL.
Teng KK, et al.
Mol Cell Neurosci. 1996;8(2-3):157-70.
Mol Cell Neurosci. 1996.
PMID: 8918832
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