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Expression of family with sequence similarity 172 member A and nucleotide-binding protein 1 is associated with the poor prognosis of colorectal carcinoma.
Liu W, Wang S, Qian K, Zhang J, Zhang Z, Liu H. Liu W, et al. Oncol Lett. 2017 Sep;14(3):3587-3593. doi: 10.3892/ol.2017.6585. Epub 2017 Jul 15. Oncol Lett. 2017. PMID: 28927116 Free PMC article.
The present study aimed to confirm the expression levels of FAM172A and nucleotide-binding protein 1 (NUBP1) in colorectal cancer (CRC) tissues and normal colorectal tissues. The impact of FAM172A and NUBP1 on the prognosis of patients with CRC was also analy …
The present study aimed to confirm the expression levels of FAM172A and nucleotide-binding protein 1 (NUBP1) in colorectal cancer …
Structure and association of ATP-binding cassette transporter nucleotide-binding domains.
Kerr ID. Kerr ID. Biochim Biophys Acta. 2002 Mar 19;1561(1):47-64. doi: 10.1016/s0304-4157(01)00008-9. Biochim Biophys Acta. 2002. PMID: 11988180 Free article. Review.
Members of this family of proteins are involved in diverse physiological processes including antigen presentation, drug efflux from cancer cells, bacterial nutrient uptake and cystic fibrosis. In order to understand more completely the role of these multidomain transporter …
Members of this family of proteins are involved in diverse physiological processes including antigen presentation, drug efflux from cance …
Determining the structure and mechanism of the human multidrug resistance P-glycoprotein using cysteine-scanning mutagenesis and thiol-modification techniques.
Loo TW, Clarke DM. Loo TW, et al. Biochim Biophys Acta. 1999 Dec 6;1461(2):315-25. doi: 10.1016/s0005-2736(99)00165-0. Biochim Biophys Acta. 1999. PMID: 10581364 Free article. Review.
The protein is important because it contributes to the phenomenon of multidrug resistance during AIDS and cancer chemotherapy. We have used cysteine-scanning mutagenesis and thiol-modification techniques to map the topology of the protein, show that both nucleotide-binding …
The protein is important because it contributes to the phenomenon of multidrug resistance during AIDS and cancer chemotherapy. We hav …
KRAS and guanine nucleotide-binding protein mutations in pancreatic juice collected from the duodenum of patients at high risk for neoplasia undergoing endoscopic ultrasound.
Eshleman JR, Norris AL, Sadakari Y, Debeljak M, Borges M, Harrington C, Lin E, Brant A, Barkley T, Almario JA, Topazian M, Farrell J, Syngal S, Lee JH, Yu J, Hruban RH, Kanda M, Canto MI, Goggins M. Eshleman JR, et al. Clin Gastroenterol Hepatol. 2015 May;13(5):963-9.e4. doi: 10.1016/j.cgh.2014.11.028. Epub 2014 Dec 4. Clin Gastroenterol Hepatol. 2015. PMID: 25481712 Free PMC article.
RESULTS: KRAS mutations were detected in pancreatic juice from larger percentages of subjects with pancreatic cancer (73%) or undergoing cancer screening (50%) than controls (19%) (P = .0005). ...CONCLUSIONS: Mutations in KRAS are detected in pancreatic juice from t …
RESULTS: KRAS mutations were detected in pancreatic juice from larger percentages of subjects with pancreatic cancer (73%) or undergo …