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Protective effects of estradiol on ethanol-induced bone loss involve inhibition of reactive oxygen species generation in osteoblasts and downstream activation of the extracellular signal-regulated kinase/signal transducer and activator of transcription 3/receptor activator of nuclear factor-kappaB ligand signaling cascade.
Chen JR, Shankar K, Nagarajan S, Badger TM, Ronis MJ. Chen JR, et al. Among authors: nagarajan s. J Pharmacol Exp Ther. 2008 Jan;324(1):50-9. doi: 10.1124/jpet.107.130351. Epub 2007 Oct 4. J Pharmacol Exp Ther. 2008. PMID: 17916759
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