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Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes.
Ai R, Laragione T, Hammaker D, Boyle DL, Wildberg A, Maeshima K, Palescandolo E, Krishna V, Pocalyko D, Whitaker JW, Bai Y, Nagpal S, Bachman KE, Ainsworth RI, Wang M, Ding B, Gulko PS, Wang W, Firestein GS. Ai R, et al. Among authors: nagpal s. Nat Commun. 2018 May 15;9(1):1921. doi: 10.1038/s41467-018-04310-9. Nat Commun. 2018. PMID: 29765031 Free PMC article.
Integration of the Transcriptome and Genome-Wide Landscape of BRD2 and BRD4 Binding Motifs Identifies Key Superenhancer Genes and Reveals the Mechanism of Bet Inhibitor Action in Rheumatoid Arthritis Synovial Fibroblasts.
Krishna V, Yin X, Song Q, Walsh A, Pocalyko D, Bachman K, Anderson I, Madakamutil L, Nagpal S. Krishna V, et al. Among authors: nagpal s. J Immunol. 2021 Jan 15;206(2):422-431. doi: 10.4049/jimmunol.2000286. Epub 2020 Dec 7. J Immunol. 2021. PMID: 33288543
Pathogenic, glycolytic PD-1+ B cells accumulate in the hypoxic RA joint.
Floudas A, Neto N, Marzaioli V, Murray K, Moran B, Monaghan MG, Low C, Mullan RH, Rao N, Krishna V, Nagpal S, Veale DJ, Fearon U. Floudas A, et al. Among authors: nagpal s. JCI Insight. 2020 Nov 5;5(21):e139032. doi: 10.1172/jci.insight.139032. JCI Insight. 2020. PMID: 33148884 Free PMC article.
Distinct stromal and immune cell interactions shape the pathogenesis of rheumatoid and psoriatic arthritis.
Floudas A, Smith CM, Tynan O, Neto N, Krishna V, Wade SM, Hanlon M, Cunningham C, Marzaioli V, Canavan M, Fletcher JM, Mullan RH, Cole S, Hao LY, Monaghan MG, Nagpal S, Veale DJ, Fearon U. Floudas A, et al. Among authors: nagpal s. Ann Rheum Dis. 2022 Aug 11;81(9):1224-1242. doi: 10.1136/annrheumdis-2021-221761. Ann Rheum Dis. 2022. PMID: 35701153 Free article.
Rheumatoid arthritis CD14+ monocytes display metabolic and inflammatory dysfunction, a phenotype that precedes clinical manifestation of disease.
McGarry T, Hanlon MM, Marzaioli V, Cunningham CC, Krishna V, Murray K, Hurson C, Gallagher P, Nagpal S, Veale DJ, Fearon U. McGarry T, et al. Among authors: nagpal s. Clin Transl Immunology. 2021 Jan 19;10(1):e1237. doi: 10.1002/cti2.1237. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33510894 Free PMC article.
The Rheumatoid Arthritis-Associated Citrullinome.
Tilvawala R, Nguyen SH, Maurais AJ, Nemmara VV, Nagar M, Salinger AJ, Nagpal S, Weerapana E, Thompson PR. Tilvawala R, et al. Among authors: nagpal s. Cell Chem Biol. 2018 Jun 21;25(6):691-704.e6. doi: 10.1016/j.chembiol.2018.03.002. Epub 2018 Apr 5. Cell Chem Biol. 2018. PMID: 29628436 Free PMC article.
Cohort profile of a US military population for evaluating pre-disease and disease serological biomarkers in rheumatoid and reactive arthritis: Rationale, organization, design, and baseline characteristics.
Porter CK, Riddle MS, Laird RM, Loza M, Cole S, Gariepy C, Alcala A, Gutierréz R, Baribaud F, Rao NL, Nagpal S. Porter CK, et al. Among authors: nagpal s. Contemp Clin Trials Commun. 2020 Jan 14;17:100522. doi: 10.1016/j.conctc.2020.100522. eCollection 2020 Mar. Contemp Clin Trials Commun. 2020. PMID: 31989058 Free PMC article.
522 results